Results 11 to 20 of about 11,335 (213)
Summary results of the 2014-2015 DARPA Chikungunya challenge
BMC Infectious Diseases, 2018 Background: Emerging pathogens such as Zika, chikungunya, Ebola, and dengue viruses are serious threats to national and global health security. Accurate forecasts of emerging epidemics and their severity are critical to minimizing subsequent mortality ...
Sara Y. Del Valle +14 more
doaj +1 more source
Cells, 2020 Despite the existence of differences in gene expression across numerous genes between males and females having been known for a long time, these have been mostly ignored in many studies, including drug development and its therapeutic use.
Cankut Çubuk +3 more
doaj +1 more source
A Mechanistic Model of the Actin Cycle [PDF]
Biophysical Journal, 2004 We have derived a broad, deterministic model of the steady-state actin cycle that includes its major regulatory mechanisms. Ours is the first model to solve the complete nucleotide profile within filaments, a feature that determines the dynamics and geometry of actin networks at the leading edges of motile cells, and one that has challenged ...
Bindschadler, M. +3 more
openaire +3 more sources
A Generalized Mechanistic Codon Model [PDF]
Molecular Biology and Evolution, 2014 Models of codon evolution have attracted particular interest because of their unique capabilities to detect selection forces and their high fit when applied to sequence evolution. We described here a novel approach for modeling codon evolution, which is based on Kronecker product of matrices.
Zaheri Maryam +2 more
openaire +5 more sources
BayCANN: Streamlining Bayesian Calibration With Artificial Neural Network Metamodeling
Frontiers in Physiology, 2021 Purpose: Bayesian calibration is generally superior to standard direct-search algorithms in that it estimates the full joint posterior distribution of the calibrated parameters.
Hawre Jalal +2 more
doaj +1 more source
Mechanistic model of hormonal contraception
PLOS Computational Biology, 2020 Contraceptive drugs intended for family planning are used by the majority of married or in-union women in almost all regions of the world. The two most prevalent types of hormones associated with contraception are synthetic estrogens and progestins. Hormonal based contraceptives contain a dose of a synthetic progesterone (progestin) or a combination of
A. Armean Wright +3 more
openaire +4 more sources
Recovery in environmental risk assessments at EFSA
EFSA Journal, 2016 EFSA performs environmental risk assessments (ERAs) for single potential stressors such as plant protection products, genetically modified organisms and feed additives and for invasive alien species that are harmful for plant health.
EFSA Scientific Committee
doaj +1 more source
Italian Journal of Agronomy, 2021 A scoping review of the relevant literature was carried out to identify the existing N recommendation systems, their temporal and geographical diffusion, and knowledge gaps. In total, 151 studies were identified and categorized.
Martina Corti +2 more
doaj +1 more source
Mechanistic Modelling of Radiation Responses [PDF]
Cancers, 2019 Radiobiological modelling has been a key part of radiation biology and therapy for many decades, and many aspects of clinical practice are guided by tools such as the linear-quadratic model. However, most of the models in regular clinical use are abstract and empirical, and do not provide significant scope for mechanistic interpretation or making ...
Stephen J. McMahon, Kevin M. Prise
openaire +3 more sources
Journal of Limnology, 2021 Process-based aquatic ecosystem models are increasingly being developed and used in freshwater ecology and other aquatic sciences, as they are powerful tools to gain a mechanistic understanding of ecological processes and inform policy and decision ...
Gregorio A. López Moreira M. +2 more
doaj +1 more source