Results 41 to 50 of about 12,181 (265)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Сельскохозяйственные машины и технологии, 2023 The paper highlights the importance of clarifying scientific terminology to delineate the exclusion of humans from technical systems, in particular the concepts such as «mechanization,» «automation,» «robotization,» and «digitalization» that are commonly
V. M. Korotchenya
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Assessment of mechanization status for some major crop value chains in Ghana
Academy Journal of Science and Engineering, 2023 Mechanization of agriculture is widely accepted as a means to raise agricultural output and ensure sufficient food supplies. Previous failed attempts to mechanize Ghana's agriculture have been linked to a failure on the part of policymakers to recognize ...
Patricia Amankwaa-Yeboah +7 more
doaj
Revista Brasileira de Engenharia Agrícola e Ambiental, 2001 Este trabalho apresenta uma proposta de desenvolvimento de um sistema informativo, projetado especificamente para o levantamento dos dados operacionais no campo, o que visa ao gerenciamento da informação na propriedade agrícola.
Gastão M. da Silveira +2 more
doaj +1 more source
Productivity and Quality Sugarcane Broth at Different Soil Management
Agronomy, 2023 The quality of sugarcane broth can be affected by soil management. In compacted soils the productivity is reduced, and the raw material is poor. This research aimed to evaluate productivity and quality of sugarcane for four soil management types: (CT ...
Murilo Battistuzzi Martins +8 more
doaj +1 more source
Mechanisms of Teratogenesis [PDF]
American Journal of Anatomy, 1972 Man’s early pictorial and written records make it clear that he was aware of and curious about the structural defects that from birth afflicted some of his fellow men. His attitudes about these congenital variants have ranged widely in different cultures: from romanticizing them in mythology, to using them as portent of coming events, to accepting them
openaire +2 more sources
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Applied Sciences, 2022 In view of the problems of rapid construction and deformation control of large cross-section tunnels in complex urban environments, the concept of “timely high-strength support” was put forward to form strong support over time and bear the load of ...
Mingli Huang +3 more
doaj +1 more source