Results 51 to 60 of about 36,809 (300)
Genome Research, 1998 A number of recent studies have provided new insights into mechanisms that regulate genomic imprinting in the mammalian genome. Regions of allele-specific differential methylation (DMRs) are present in all imprinted genes examined. Differential methylation is erased in germ cells at an early stage of their development, and germ-line-specific ...
Constância, Miguel +3 more
openaire +4 more sources
Сельскохозяйственные машины и технологии, 2023 The paper highlights the importance of clarifying scientific terminology to delineate the exclusion of humans from technical systems, in particular the concepts such as «mechanization,» «automation,» «robotization,» and «digitalization» that are commonly
V. M. Korotchenya
doaj +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Revista Brasileira de Engenharia Agrícola e Ambiental, 2001 Este trabalho apresenta uma proposta de desenvolvimento de um sistema informativo, projetado especificamente para o levantamento dos dados operacionais no campo, o que visa ao gerenciamento da informação na propriedade agrícola.
Gastão M. da Silveira +2 more
doaj +1 more source
Productivity and Quality Sugarcane Broth at Different Soil Management
Agronomy, 2023 The quality of sugarcane broth can be affected by soil management. In compacted soils the productivity is reduced, and the raw material is poor. This research aimed to evaluate productivity and quality of sugarcane for four soil management types: (CT ...
Murilo Battistuzzi Martins +8 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Assessment of mechanization status for some major crop value chains in Ghana
Academy Journal of Science and Engineering, 2023 Mechanization of agriculture is widely accepted as a means to raise agricultural output and ensure sufficient food supplies. Previous failed attempts to mechanize Ghana's agriculture have been linked to a failure on the part of policymakers to recognize ...
Patricia Amankwaa-Yeboah +7 more
doaj
Applied Sciences, 2022 In view of the problems of rapid construction and deformation control of large cross-section tunnels in complex urban environments, the concept of “timely high-strength support” was put forward to form strong support over time and bear the load of ...
Mingli Huang +3 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Mechanisms of Teratogenesis [PDF]
American Journal of Anatomy, 1972 Man’s early pictorial and written records make it clear that he was aware of and curious about the structural defects that from birth afflicted some of his fellow men. His attitudes about these congenital variants have ranged widely in different cultures: from romanticizing them in mythology, to using them as portent of coming events, to accepting them
openaire +2 more sources