Results 301 to 310 of about 35,268 (338)
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2023
Growth, motion, morphogenesis, and self-organization are features common to all biological systems. Harnessing chemical energy allows biological cells to function out of thermodynamic equilibrium and to alter their number, size, shape, and location. For example, the zygote that results when a mammalian egg and sperm cell fuse divides to form a ball of ...
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Growth, motion, morphogenesis, and self-organization are features common to all biological systems. Harnessing chemical energy allows biological cells to function out of thermodynamic equilibrium and to alter their number, size, shape, and location. For example, the zygote that results when a mammalian egg and sperm cell fuse divides to form a ball of ...
openaire +2 more sources
Mechanobiology of organelles: illuminating their roles in mechanosensing and mechanotransduction.
Trends in Cell Biology, 2023Mechanobiology studies the mechanisms by which cells sense and respond to physical forces, and the role of these forces in shaping cells and tissues themselves. Mechanosensing can occur at the plasma membrane, which is directly exposed to external forces,
Santosh Phuyal +3 more
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Acta Biomaterialia, 2023
Mechanical cues in the cell microenvironment such as those from extracellular matrix properties, stretching, compression and shear stress, play a critical role in maintaining homeostasis.
Ning Xie +11 more
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Mechanical cues in the cell microenvironment such as those from extracellular matrix properties, stretching, compression and shear stress, play a critical role in maintaining homeostasis.
Ning Xie +11 more
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Mechanobiology of the blood-brain barrier during development, disease and ageing
Nature CommunicationsThe blood-brain barrier (BBB) preserves brain health through selective permeability, and its disruption is a hallmark of many neurological disorders. Mechanical stimuli such as shear stress and cyclic strain are increasingly recognised to influence BBB ...
Simon Konig +4 more
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The mechanobiology of biomolecular condensates
Biophysical ReviewsThe central goal of mechanobiology is to understand how the mechanical forces and material properties of organelles, cells, and tissues influence biological processes and functions.
Neus Sanfeliu-Cerdán, Michael Krieg
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Biomechanics and Mechanobiology of Additively Manufactured Porous Load-Bearing Bone Implants.
SmallGiven that they can replicate both the biomechanical and mechanobiological functions of natural bone, metal additively manufactured porous load-bearing bone implants present a significant advancement in orthopedic applications. Additive manufacturing (AM)
Yuan Jin +4 more
semanticscholar +1 more source
Aging Clinical and Experimental Research, 2013
Bone is a tissue that dynamically adapts mass and architecture to the mechanical loads that occur in daily life in a world with gravity. Bone architecture and mass are influenced by the applied tension peak, whereas the bone formation rate is modulated by the stimulus frequency.
IOLASCON, Giovanni +2 more
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Bone is a tissue that dynamically adapts mass and architecture to the mechanical loads that occur in daily life in a world with gravity. Bone architecture and mass are influenced by the applied tension peak, whereas the bone formation rate is modulated by the stimulus frequency.
IOLASCON, Giovanni +2 more
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Squishy matters – Corneal mechanobiology in health and disease
Progress in retinal and eye researchThe cornea, as a dynamic and responsive tissue, constantly interacts with mechanical forces in order to maintain its structural integrity, barrier function, transparency and refractive power.
S. Thomasy +4 more
semanticscholar +1 more source
Estrogen and estrogen receptors mediate the mechanobiology of bone disease and repair.
BoneIt is well understood that the balance of bone formation and resorption is dependent on both mechanical and biochemical factors. In addition to cell-secreted cytokines and growth factors, sex hormones like estrogen are critical to maintaining bone health.
V. Shi, Elise F. Morgan
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2022
Quantitative understanding of how cells sense their surrounding physical environment and how that environment determines their fate will be indispensable for designing cell-culture scaffolds for regenerative medicine in the future. Supported by the rapid progress of microfabrication technologies, recent studies in mechanobiology have revealed that even
Ryosuke Matsuzawa +3 more
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Quantitative understanding of how cells sense their surrounding physical environment and how that environment determines their fate will be indispensable for designing cell-culture scaffolds for regenerative medicine in the future. Supported by the rapid progress of microfabrication technologies, recent studies in mechanobiology have revealed that even
Ryosuke Matsuzawa +3 more
openaire +1 more source