Results 91 to 100 of about 16,570 (284)

Mechanophore activation enhanced by hydrogen bonding of diarylurea motifs: An efficient supramolecular force‐transducing system

Aggregate, 2021
Macromolecules are efficient as mechanical transducers for mechanically induced chemical bond cleavage reactions. Although various classes of polymers have been studied as effective mechanical‐force transducers for mechanophores, alternatives to polymer ...
Jumpei Kida, Daisuke Aoki, Hideyuki Otsuka   +2 more
doaj   +1 more source

CD28‐Targeted Enzyme‐Responsive Conformation‐Switching Peptide Self‐Assembly for Selective T‐Cell Acute Lymphoblastic Leukemia (T‐ALL) Therapy

Advanced Science, EarlyView.
We developed the enzyme‐responsive peptide SAp‐CD28 to selectively target CD28‐overexpressing T‐ALL cells. Following phosphatase‐mediated activation, SAp‐CD28 undergoes conformational switching and nanooligomerization, resulting in the disruption of CD28 downstream signaling.
Jun Li, Ziyu Jia, Dekun Li, Zhi‐Wen Hu, Yinghao Ding, Shengyi Zhang, Shengkun Tuo, Zhimou Yang, Huisheng Fu, Ling Wang, Man‐Di Wang   +10 more
wiley   +1 more source

Mechanochemical processing of limestone and sodium carbonate toward the development of reactive carbonate-based binder

Next Materials
This study investigates the mechanochemical activation of limestone, with and without 10 wt% sodium carbonate, as a low-energy approach to enhancing the reactivity of carbonate-based binder systems. High-energy ball milling was applied for durations of 2 
Roz-Ud-Din Nassar, Anagi Balachandra, Shumayal Nassar, Parviz Soroushian   +3 more
doaj   +1 more source

CO2 Hydrogenation Induced by Mechanochemical Activation of Olivine With Water Under CO2 Atmosphere

Frontiers in Energy Research, 2019
A study on the mechanochemical activation of the olivine in presence of H2O and under CO2 atmosphere have been approached, focusing both on the structural nature of the transformation and the conversion of CO2 to methane and light hydrocarbons.
Valeria Farina, Nadia S. Gamba, Fabiana Gennari, Sebastiano Garroni, Francesco Torre, Alessandro Taras, Stefano Enzo, Gabriele Mulas   +7 more
doaj   +1 more source

Effects of demographic noise on the synchronization of a metapopulation in a fluctuating environment [PDF]

, 2011
We use the theory of noise-induced phase synchronization to analyze the effects of demographic noise on the synchronization of a metapopulation of predator-prey systems within a fluctuating environment (Moran effect).
Bressloff, P. C., Lai, Y. M., Newby, J. M.   +2 more
core   +2 more sources

Modular Generation of Alkyl Selenyl Radicals for the Synthesis of Alkyl Selenides via a Mechanochemical Approach

Advanced Science, EarlyView.
We present a mechanochemical, radical‐mediated hydroselenation of alkenes under ambient conditions. This method modularly generates alkyl selenyl radicals from elemental selenium and alkyl (pseudo)halides, utilizing PhSiH3 and H2O as hydrogen atom donors, with the water likely originating from the air and/or trace water present in the reagents ...
Xiaochun He, Yu Zhou, Fei Zhou, Zixi Ai, Peiyu Hu, Xuemei Zhang, Xiaofeng Wei, Gui‐Juan Cheng, Zhong Lian   +8 more
wiley   +1 more source

Combined mechanochemical and solid CO2 treatment for enhanced carbon uptake and performance of slag-based geopolymers

Journal of CO2 Utilization
In response to the high carbon emissions from cement production, carbon mineralization for CO2 sequestration and alternative cementitious materials have gained attention.
Sixiang Kang, Chenhao Song, Jize Wang, Wenda Wu, Tao Wang, Leiming Ling, Huaqiang Sun, Ying Lou, Xuefang Wang, Liwei Xu   +9 more
doaj   +1 more source

Solvent-Free Copper-Catalyzed Azide-Alkyne Cycloaddition under Mechanochemical Activation

Molecules, 2015
The ball-mill-based mechanochemical activation of metallic copper powder facilitates solvent-free alkyne-azide click reactions (CuAAC). All parameters that affect reaction rate (i.e., milling time, revolutions/min, size and milling ball number) have been
Laura Rinaldi, Katia Martina, Francesca Baricco, Laura Rotolo, Giancarlo Cravotto   +4 more
doaj   +1 more source

Dynamin recruitment by clathrin coats: a physical step? [PDF]

, 2003
Recent structural findings have shown that dynamin, a cytosol protein playing a key-role in clathrin-mediated endocytosis, inserts partly within the lipid bilayer and tends to self-assemble around lipid tubules. Taking into account these observations, we
Dommersnes, P. -G., Fournier, J. -B., Galatola, P.   +2 more
core   +2 more sources

Piezo1 Channel Mediates Mechanically Programmable Drug Delivery to Potentiate Intravesical Chemotherapy

Advanced Science, EarlyView.
This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma, Xing Li, Minxuan Jing, Zezhong Yang, Jiale He, Jianpeng Li, Xiao Liang, Yunzhong Jiang, Rou Huang, Yuanquan Zhang, Yuanchun Pu, Jiawei Xiu, Yutong Chen, Kaibo Mi, Pu Zhang, Lei Wang, Jinhai Fan   +16 more
wiley   +1 more source