Results 41 to 50 of about 3,292 (182)

Increase of solubility and transmembrane permeability of niclosamide from its mechanochemically synthesized solid dispersions

Chimica Techno Acta, 2023
More than 4.5 billion people worldwide are affected by parasitic diseases, with helminth infections accounting for 99% of the total number. Niclosamide (NS) is a weakly acidic active pharmaceutical ingredient (API) used to treat helminth infections ...
Elizaveta S. Meteleva, Elizaveta A. Roenko, Nikolay E. Polyakov   +2 more
doaj   +1 more source

Calcium‐Mechanochemistry Enabled Ketone Synthesis From Organic Iodides and Carboxylic Acids

Advanced Science, EarlyView.
Mechanochemically generated organocalcium species display unusual chemoselectivity toward carboxylates, enabling direct ketone synthesis without overaddition. Ball milling activates commercial calcium metal under ambient, solvent‐minimized conditions, providing a broad substrate scope, high functional‐group tolerance, and a practical one‐step ...
Mengyao Pei, Zekun Yang, Xueyan Yang, Yufang Yang, Yangyang Shen, Jiemin Wang, Peile Ma, Zezhu Li, Xiaoliang Zheng, Xiaofeng Wei   +9 more
wiley   +1 more source

Linking mechanochemistry with the green chemistry principles: Review article

Heliyon
The need to explore contemporary alternatives for industrial production has driven the development of innovative techniques that address critical limitations linked to traditional batch mechanochemistry.
Sergi Arfelis, Ana I. Martín-Perales, Remy Nguyen, Antonio Pérez, Igor Cherubin, Christophe Len, Irene Malpartida, Alba Bala, Pere Fullana-i-Palmer   +8 more
doaj   +1 more source

Thermal Properties and Ionic Conductivity of Tetra-n-Butylammonium Perchlorate

Crystals, 2022
The thermal parameters of the phase transitions and transport properties of tetra-n-butylammonium (TBA) perchlorate (n-C4H9)4NClO4 (TBAClO4) were investigated. TBAClO4 has a polymorphous transition at 330 K and melts at 487 K.
Nikolai F. Uvarov, Nargiz B. Asanbaeva, Artem S. Ulihin, Yulia G. Mateyshina, Konstantin B. Gerasimov   +4 more
doaj   +1 more source

Mechanochemical Piezoelectric Catalysis: Advancing the Hydrogenation of Alkenes

Advanced Science, EarlyView.
This study presents mechanochemical piezoelectric catalysis for alkene hydrogenation, eliminating the need for transition metals, H2, and solvents. The method effectively hydrogenates diverse activated and unactivated alkenes and shows potential for modifying bioactive molecules in pharmaceuticals.
Zixi Ai, Mengting Liu, Xiaohong Wang, Xiaochun He, Xuemei Zhang, Zhong Lian   +5 more
wiley   +1 more source

Mechanochemistry: A Force of Synthesis [PDF]

ACS Central Science, 2016
The past decade has seen a reawakening of solid-state approaches to chemical synthesis, driven by the search for new, cleaner synthetic methodologies. Mechanochemistry, i.e., chemical transformations initiated or sustained by mechanical force, has been advancing particularly rapidly, from a laboratory curiosity to a widely applicable technique that not
Jean-Louis Do, Tomislav Friščić
openaire   +3 more sources

Strain Release of 1‐Azabicyclo[1.1.0]butanes as a Gateway to Highly Functionalized Azetidines: New Strategies and Structural Motifs

Chemistry – A European Journal, EarlyView.
Over the past decade, the interest in azetidines has continuously risen, by virtue of their highly appealing pharmaceutical properties. Monocyclic, spirocyclic, and bridged azetidines can be accessed by leveraging 1‐azabicyclo[1.1.0]butanes as precursors.
Yuri Gelato, Philipp Natho, Marco Colella, Renzo Luisi   +3 more
wiley   +1 more source

Copolymer of VDF/TFE as a Promising Polymer Additive for CsH₂PO₄-Based Composite Electrolytes

Membranes, 2023
The composite polymer electrolytes (1-x)CsH2PO4-xF-2M (x = 0–0.3) have been first synthesized and their electrotransport, structural, and mechanical properties were investigated in detail by impedance, FTIR spectroscopy, electron microscopy, and X-ray ...
Yuri Kungurtsev, Irina Bagryantseva, Valentina Ponomareva   +2 more
doaj   +1 more source

Mechanochemical Amidation Mediated by 1,1’‐Oxalyldiimidazole for the Synthesis of Agrochemicals

Chemistry – A European Journal, EarlyView.
Mechanochemical amidation using 1,1'‐oxalyldiimidazole (ODI) overcomes limitations of 1,1’‐carbonyl diimidazole (CDI) as coupling agent by enabling the efficient mechanochemical synthesis of three marketed agrochemicals from deactivated carboxylic acids.
Andrea Casagrande, Rubén Solorzano‐Rodriguez, Maria Carta, Francesco Delogu, Joris Vezzani, Allan Niidu, Evelina Colacino   +6 more
wiley   +1 more source

High-Conductive CsH₂PO₄ Membranes with PVDF-Based Polymers Additives

Membranes, 2023
The study is devoted to one of the important problems of hydrogen energy—the comparative analysis and creation of novel highly conductive and durable medium-temperature proton membranes based on cesium dihydrogen phosphate and fluoropolymers.
Irina Bagryantseva, Valentina Ponomareva, Yuri Kungurtsev   +2 more
doaj   +1 more source