Results 141 to 150 of about 19,675 (276)

Peripheral κ opioid receptor in pain and inflammation: From molecular signalling and gene expression to drug discovery

British Journal of Pharmacology, EarlyView.
The κ opioid receptor (κ receptor, KOR) is a G protein‐coupled receptor with well established roles in analgesia and immune modulation. Although historically studied primarily in the central nervous system (CNS), growing evidence indicates that κ signalling in peripheral tissues plays an important role in regulating pain, inflammation and immune ...
Rumsha Khan, Elena C. A. Becker, Boglarka B. Bata, Christian W. Gruber   +3 more
wiley   +1 more source

Oral Fine Motor Control in Patients With Anterior Maxillary Single Implants, Freestanding Teeth and Teeth Connected in 3‐Unit Bridges: An Experimental In Vivo Study

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives The oral fine motor control is compromised in patients with full‐arch, bimaxillary bridges compared to those with natural teeth. No previous studies have examined the differences between the prosthetic treatments small anterior bridges and single anterior implants (SI). The aim of the study was to evaluate oral fine motor control in
Nicole Winitsky, Aron Naimi‐Akbar, Jan‐Ivan Smedberg, Anastasios Grigoriadis   +3 more
wiley   +1 more source

BDNF plays a role in differentiation of the zebrafish lateral line mechanoreceptors.

, 2015
Lateral line development of 48 hpf zebrafish embryos injected with mRNA encoding different forms of BDNF. A–B—SqET20 transgenic embryo expressing GFP in the mantle cells of neuromasts, mechanoreceptors are stained with DASPEI: A—control, B—mature BDNF ...
Eugene V. Gasanov (280583), Vladimir P. Korzh (699609), Lola M. Rafieva (699608)   +2 more
core   +1 more source

A noncanonical role for Jagged1 in endothelial mechanotransduction

The FEBS Journal, EarlyView.
This study reveals a noncanonical role for Jagged1 in endothelial mechanotransduction. Shear stress modulates Jagged1 expression and subcellular localization. Loss of Jagged1 attenuates mechanotransduction and reduces Src, VEGFR2, and ERK signaling. Direct mechanical stimulation of Jagged1 induces activation of these signaling pathways.
Freddy Suarez Rodriguez, Noora Virtanen, Elmeri Kiviluoto, Rob C. H. Driessen, Feihu Zhao, Carlijn V. C. Bouten, Oscar M. J. A. Stassen, Cecilia M. Sahlgren   +7 more
wiley   +1 more source

Immunohistochemical Detection of Tentonin-3/TMEM150C in Human Dorsal Root Ganglion, Cutaneous End-Organ Complexes, and Muscle Spindles

Brain Sciences
Background/Objectives: Tentonin-3/TMEM150C is a pore-forming protein of a mechanically activated channel recently identified that typically displays rapid activation followed by slow inactivation.
Iván Suazo, Yolanda García-Mesa, José Martín-Cruces, Patricia Cuendias, Teresa Cobo, Olivia García-Suárez, José A. Vega   +6 more
doaj   +1 more source

Effects of leptin on cat intestinal vagal mechanoreceptors

, 2002
International audienceVagal afferent nerve fibres are involved in the transmission to the central nervous system of information relating to food intake and immune reactions.
Bouvier, Michel, Stéphanie Gaigé, Gaigé, Stéphanie, Anne Abysique, Michel Bouvier, Abysique, Anne   +5 more
core   +1 more source

Bone health in adults with non‐ambulatory neuromuscular disorders: scoping review of risk factors, diagnosis and management

Internal Medicine Journal, EarlyView.
Abstract Background Non‐ambulatory adults have an increased risk of osteoporosis and fractures due to reduced weight‐bearing and diminished neuromuscular stimulation, resulting in substantial morbidity and mortality. Aims This scoping review aimed to systematically evaluate risk factors, diagnostic indicators and management strategies for optimising ...
Thomas Bailey, Carolyn Droste, John A. Eisman, Steven G. Faux, Arnagretta Hunter   +4 more
wiley   +1 more source

Review of mechanoreceptors and the neural processing of touch sensations

This report provides an overview of mechanoreceptors and their role in the somatosensory system, emphasizing their structural characteristics, response properties, and functional specialization.
Kardashina, Tatiana
core  

Systematic Review Evaluating the Influence of Veneering Design on the Clinical Outcome of All‐Ceramic Implant‐Supported 3–4 Units and Full Arch Fixed Dental Prostheses

Journal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objective To systematically assess survival, failure, and complication rates of all‐ceramic implant‐supported monolithic and micro‐veneered FDPs (i‐FDPs) in partially/completely edentulous patients compared to veneered restorations. Materials and Methods An electronic search identified prospective clinical studies on all‐ceramic i‐FDPs with at
Shaza Bishti, Stefan Wolfart, Marcel Zwahlen, Lukas Waltenberger   +3 more
wiley   +1 more source

Post‐hatching development of the remote‐tactile bill‐tip organ in precocial shorebirds (Scolopacidae)

Journal of Anatomy, EarlyView.
Juvenile scolopacid shorebirds possess well‐developed osteological correlates of tactile bill‐tip organs, indicating sensory systems for remote‐touch foraging are present from early life. Ontogenetic changes in bill‐tip morphology suggest ecological specialisation and interspecific variation develop later, after fledging in these highly precocial ...
Carla J. du Toit, Anyaise Green, Daniel J. Field   +2 more
wiley   +1 more source