Results 161 to 170 of about 17,423 (254)

Modeling based insights into mechanical dysfunction in esophageal motility disorders. [PDF]

PLoS Comput Biol
Elisha G, Halder S, Liu X, Carlson DA, Kahrilas PJ, Pandolfino JE, Patankar NA.   +6 more
europepmc   +1 more source

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

The Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise, Qinglu Li, Mary G. Garry   +2 more
wiley   +1 more source

Histomorphological and ultrastructural analysis of vibrissal follicle-sinus complexes in the dog (Canis lupus familiaris). [PDF]

PLoS One
Müller HE, Fiedler S, Schwarz E, Bliemel S, Franzmeier S, Fuchs-Baumgartinger A, Gerics B, Pöpperl P, Wannemacher R, Reese S, Döring D, Matiasek K, Blutke A.   +12 more
europepmc   +1 more source

Hypoxia‐induced vulnerability of the somatosensory nervous system

The Journal of Physiology, EarlyView.
Abstract figure legend Sensory neurons are highly energy dependent and rely on sufficient oxygen availability to maintain metabolic stability and effective neurocommunication. Within the somatosensory system, even modest reductions in tissue oxygen tension impair neuronal respiration, forcing a shift toward less efficient metabolic pathways that ...
Jack Corbett, Richard P. Hulse
wiley   +1 more source

Low‐threshold cutaneous mechanoreceptors on the foot sole have enhanced sensitivity when skin temperature is elevated

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustration of microneurography recordings used to examine the effects of local skin heating on cutaneous mechanoreceptor responses in the human foot (left panel). A microelectrode inserted into a peripheral nerve records single‐unit activity from tactile afferent fibres while controlled mechanical stimuli are applied ...
Erika E. Howe, Michael Apollinaro, Joanna Reeves, Christopher Nester, Leah R. Bent   +4 more
wiley   +1 more source

Does Stimulation of Plantar Mechanoreceptors Alter Visual Spatial Localization? [PDF]

J Funct Morphol Kinesiol
Villeneuve P, Viseux F, Parreira R, Bucci MP.   +3 more
europepmc   +1 more source

Breathing‐evoked potentials in humans during wakefulness and sleep

The Journal of Physiology, EarlyView.
Abstract figure legend Quiet natural breathing at rest elicits structured breathing‐evoked potentials (BEPs) detectable in scalp EEG. Left, respiratory cycles were identified from the nasal pressure signal and used to time‐lock EEG averaging. Right, the resulting BEPs persist across wakefulness and all sleep stages, including non‐rapid eye movement ...
Léo Grassion, Thomas Andrillon, Marie‐Cécile Niérat, Nicolas Wattiez, Maxime Patout, Jessica Njlagni Voutsa, Delphine Oudiette, Isabelle Arnulf, Jésus Gonzalez‐Bermejo, Thomas Similowski   +9 more
wiley   +1 more source

Synchrony within Aβ mechanoreceptor subtypes governs signal propagation to primary somatosensory cortex

The Journal of Physiology, EarlyView.
Abstract figure legend We used an optogenetic gain‐of‐function manipulation to investigate how sensory signals from two subtypes of Aβ low threshold mechanoreceptors (LTMRs) contribute to the cortical representation of touch. CatCh, a sensitive and fast channelrhodopsin variant, enables pulsed‐light generation of high‐frequency action potential trains ...
Wanyi Liu, Andrew E. Worthy, Alan J. Emanuel   +2 more
wiley   +1 more source

Neuro-skeletal units and Smart Analgesia: reprogramming sensory neurons for fracture repair. [PDF]

Mil Med Res
Bai L, Su JC.
europepmc   +1 more source