Results 171 to 180 of about 21,189 (283)

Anatomical and functional mapping of vagal nociceptive sensory nerve subsets innervating the mouse lower airways by intersectional genetics

The Journal of Physiology, EarlyView.
Abstract figure legend We used an intersectional approach with recombinase‐expressing mice and adeno‐associated virus to map and modulate distinct nociceptive afferents in the vagal ganglia. TRPV1+P2X2+ neurons resided in the nodose ganglion (N), innervated the lungs (many projected into the alveoli) but not the trachea, and projected to the nucleus ...
Mayur J. Patil, Justin Shane Hooper, Seol‐Hee Kim, Parmvir K. Bahia, Nika Pavelkova, Sanjay S. Nair, Teresa S. Darcey, Karina V. Lurye, Meghana Madaram, Jailene Fiallo, Stephen H. Hadley, Thomas E. Taylor‐Clark   +11 more
wiley   +1 more source

Modeling based insights into mechanical dysfunction in esophageal motility disorders. [PDF]

PLoS Comput Biol
Elisha G, Halder S, Liu X, Carlson DA, Kahrilas PJ, Pandolfino JE, Patankar NA.   +6 more
europepmc   +1 more source

Elevated carotid body tonic activity contributes to ventilatory acclimatization and de‐acclimatization to high altitude at rest and during exercise

The Journal of Physiology, EarlyView.
Abstract figure legend Participants spent 13 days at high altitude (3800 m), where the reduced inspired oxygen pressure (↓PiO2$ \downarrow {P_{{\mathrm{i}}{{\mathrm{O}}_2}}}$) which elicited ventilatory acclimatization and increased inhibition of ventilation by transient hyperoxia (ΔV̇E$\Delta {\dot V_{\mathrm{E}}}$).
Ayechew A. Getu, L. Madden Brewster, Travis D. Gibbons, James D. Anholm, Michael Stembridge, Philip N. Ainslie, Jay M. J. R. Carr   +6 more
wiley   +1 more source

Does Stimulation of Plantar Mechanoreceptors Alter Visual Spatial Localization? [PDF]

J Funct Morphol Kinesiol
Villeneuve P, Viseux F, Parreira R, Bucci MP.   +3 more
europepmc   +1 more source

Mechanical sensitization of sensory afferents after passive transfer of fibromyalgia IgG

The Journal of Physiology, EarlyView.
Abstract figure legend In addition to widespread pain and fatigue, people with fibromyalgia (FM) experience sensory abnormalities and report lingering, painful sensations after touch or mechanical probing of the skin. Administration of IgG purified from FM patients to mice transfers symptoms and signs of FM.
Mathilde R. Israel, Nisha Vastani, Clive Gentry, Andreas Goebel, Stuart Bevan, David A. Andersson   +5 more
wiley   +1 more source

Mechanosensory encoding of surface mechanics optimizes locomotion. [PDF]

Nat Commun
Pidde A, Porta-de-la-Riva M, Agazzi C, Martínez-Fernández C, Lorrach A, Bijalwan A, Sanfeliu-Cerdán N, Calatayud-Sanchez A, Torralba-Sales E, Das R, Muñoz JJ, Krieg M.   +11 more
europepmc   +1 more source

Variation in glabrous skin physiology across anatomical locations on the human hand

The Journal of Physiology, EarlyView.
Abstract figure legend We compared the physiological and morphological characteristics of glabrous and hairy skin for different anatomical positions in a study with 60 participants (1). Non‐invasive techniques were applied to study skin hydration, skin deformability and stratum corneum thickness (2).
Victor Hugo Pacagnelli Infante, Roland Bennewitz, Martina C. Meinke   +2 more
wiley   +1 more source

Neuro-skeletal units and Smart Analgesia: reprogramming sensory neurons for fracture repair. [PDF]

Mil Med Res
Bai L, Su JC.
europepmc   +1 more source

Vibrotactile intensity perception: Predominant influence of afferents recruited remote from stimulus site

The Journal of Physiology, EarlyView.
Abstract figure legend We delivered trains of brief mechanical pulses to the fingertips of subjects to investigate vibrotactile intensity perception. Some stimuli consisted of bursts of up to four pulses. Simulated responses of the tactile afferent population across the hand revealed that afferents innervating the skin directly under the probe reliably
Kevin K. W. Ng, Ingvars Birznieks, Richard M. Vickery   +2 more
wiley   +1 more source

Marked C‐tactile afferent suppression by a plastic film does not proportionately diminish pleasantness of gentle brushing

The Journal of Physiology, EarlyView.
Abstract figure legend Human skin contains several classes of mechanoreceptive afferents that encode mechanical stimulation. For example, C‑tactile (CT) afferents are suggested to signal the pleasant aspects of gentle touch and are activated effectively by slow brushing of hairy skin.
Johan Nikesjö, Saad S. Nagi, Ewa Jarocka, Kevin K. W. Ng, Maja Fältskytt, Andrew Marshall, Sarah McIntyre, Gregory J. Gerling, Håkan Olausson   +8 more
wiley   +1 more source