Results 181 to 190 of about 17,423 (254)

Bioadhesive‐Integrated 3D‐Printed Multilayer Scaffolds Secure a Mechanically‐Stable Osteoimmune Niche for Enhanced Bone Augmentation

open access: yesAdvanced Science, Volume 13, Issue 61, 3 November 2026.
A 3D‑printed multilayer adhesive scaffold, firmly anchored to bone defects by simple finger pressing, suppresses micromotion and secures mechanical stability of the osteogenic niche. This stabilization likely contributes to the enhanced bone augmentation by fostering a pro‑regenerative mechano‐immune profile—characterized by M2‑like macrophage ...
Delu Zhao   +7 more
wiley   +1 more source

Targeting CXCR2 in Nociceptive Sensory Neurons Offers Novel Therapeutic Potentials for Postoperative Pain

open access: yesAdvanced Science, Volume 13, Issue 61, 3 November 2026.
Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan   +10 more
wiley   +1 more source

An Innervated Human Skin Equivalent that Electrically Encodes Mechanical and Thermal Stimuli

open access: yesAdvanced Science, Volume 13, Issue 61, 3 November 2026.
An innervated human skin equivalent is integrated with high‐density microelectrode arrays to reveal how engineered free nerve ending–like structures translate touch and temperature into electrical codes. Mechanical indentation and thermal stimulation engage the engineered somatosensory circuitry and evoke distinct firing and waveform signatures ...
Daniele Bellantoni   +6 more
wiley   +1 more source

Beyond the Larynx: New Insights Into Upper Airway Responses to Mechanical Insufflation–Exsufflation

open access: yesRespirology Case Reports, Volume 14, Issue 11, November 2026.
Upper airway responses to mechanical insufflation–exsufflation extend beyond the larynx and are strongly influenced by device settings and cervical posture. Transnasal flexible laryngoscopy and videofluoroscopy revealed that lower inspiratory flow and shorter expiratory time preserved airway patency and minimized oesophageal insufflation in bulbar ALS.
Alessandra Carneiro Dorça   +4 more
wiley   +1 more source

Editorial: Vibratory therapy: impacts on endocrine disorders. [PDF]

open access: yesFront Endocrinol (Lausanne)
Bernardo-Filho M   +3 more
europepmc   +1 more source

Cortical Adaptation to Muscle Fatigue Does Not Alter Early Proprioceptive Processing in Primary Sensorimotor Cortex

open access: yesEuropean Journal of Neuroscience, Volume 64, Issue 9, November 2026.
Cortical proprioceptive responses to passive ankle‐joint movement are negligibly affected by muscle fatigue. Intriguingly, fatigue‐induced increases in alpha and beta power extend beyond the SM1 foot region to bilateral hand regions, which may facilitate more focused lower‐limb proprioceptive processing, thus compensating for asynchronous ...
Junru Chen   +4 more
wiley   +1 more source

GLP‐1 Receptor Agonists and Weight Loss: A Critical Review of Mechanisms

open access: yesObesity Reviews, Volume 27, Issue 11, November 2026.
ABSTRACT GLP‐1 receptor agonist medications have the potential to promote marked weight loss, but maximal and sustained benefit may be compromised by poor compliance and cessation of use. Development of next‐generation medications that address current obstacles to effective use and development of effective adjunct treatments will benefit from better ...
Giorgia Rutigliani   +8 more
wiley   +1 more source

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