Results 181 to 190 of about 5,291 (227)
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Hyperbaric Oxygenation and Mechlorethamine Effectiveness
Archives of Surgery, 1963In order to test one of the possible radiomimetic qualities of alkylating agents, we have studied the influence of hyperbaric oxygen on the tumoricidal action of mechlorethamine (nitrogen mustard) in spontaneous mammary tumors of heterozygous, randomly bred Swiss-Webster mice.
R P, LEATHER, C, ECKERT
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Archives of Surgery, 1964
The use of chemotherapeutic agents as an adjunct to operative management of malignant disease is receiving considerable attention in current cancer research. Since the effects of these highly toxic drugs are not entirely limited to neoplastic tissue, however, knowledge of their effects on normal healing of wounds would be valuable.
C G, LONGENECKER, E T, KREMENTZ
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The use of chemotherapeutic agents as an adjunct to operative management of malignant disease is receiving considerable attention in current cancer research. Since the effects of these highly toxic drugs are not entirely limited to neoplastic tissue, however, knowledge of their effects on normal healing of wounds would be valuable.
C G, LONGENECKER, E T, KREMENTZ
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Blood
Background: Valchlor (mechlorethamine gel) is a topical chemotherapy used to treat cutaneous T-cell lymphoma (CTCL). Despite its well-established role in CTCL treatment, limited data exist on its real-world use and cost trends across different ...
Joshua Kent +4 more
semanticscholar +1 more source
Background: Valchlor (mechlorethamine gel) is a topical chemotherapy used to treat cutaneous T-cell lymphoma (CTCL). Despite its well-established role in CTCL treatment, limited data exist on its real-world use and cost trends across different ...
Joshua Kent +4 more
semanticscholar +1 more source
Topical mechlorethamine therapy for mycosis fungoides
British Journal of Dermatology, 1977Patients with limited skin involvement by mycosis fungoides were treated with daily topical mechlorethamine. Seven of thirteen patients had a complete remission of diseases. Six of these seven experienced a contact dermatitis and four underwent a successful topical desensitization programme.
N M, Price +4 more
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Cyclophosphamide/Mechlorethamine/Prednisone/Procarbazine/Vincristine
Definitions, 2020openaire +2 more sources
Topical therapy of psoriasis with mechlorethamine.
Archives of dermatology, 1972Aqueous solutions of mechlorethamine (Mustargen) hydrochloride (0.055 to 0.00625%) have been used in courses of seven to ten days on lesions of psoriasis in 42 patients. A significant involutionary effect was obtained with the 0.0125% to 0.05% concentrations, particularly on the trunk. The rate of contact sensitization ranged from 50% to more than 80%,
H S, Zackheim +3 more
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Bone Marrow Protection in Mechlorethamine (Nitrogen Mustard) Therapy
Archives of Surgery, 1962The hematologic effects of mechlorethamine hydrochloride (nitrogen mustard) limit the dose employed when this drug is used for chemotherapy of advanced cancer. Although other toxicities are recognized, e.g., of the intestinal and central nervous system, they represent effects at higher dosage levels than are ordinarily used.
D G, MILLER, W, LAWRENCE
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Counteraction of leukopenia caused by mechlorethamine and azathioprine
Journal of Surgical Oncology, 1971AbstractPCO, a deproteinized yeast extract of low toxicity, increases tissue respiration, offsets the toxicity of mechlorethamine hydrochloride (HN2) for mice with maintenance of antineoplastic activity in the systems studied, and is a useful adjuvant to azathioprine in dog renal allografts. The two latter effects appear to be related to the ability of
E S, Cook, L G, Nutini
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Mechlorethamine Hydrochloride Solutions and Ointment
Archives of Dermatology, 1980• Solutions of mechlorethamine hydrochloride used to treat patients with mycosis fungoides and psoriasis are stable for many months, especially when they are refrigerated. This fact should make the use of this treatment more convenient. On the other hand, the risk of cancer induction from such use should be appreciated.
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Bioconjugate chemistry, 2018
Many strategies for the detection of nucleic acid sequence rely upon Watson-Crick hybridization of a probe strand to the target strand, but the reversible nature of nucleic acid hybridization presents an inherent challenge: short probes that provide high
Ruicheng Shi +4 more
semanticscholar +1 more source
Many strategies for the detection of nucleic acid sequence rely upon Watson-Crick hybridization of a probe strand to the target strand, but the reversible nature of nucleic acid hybridization presents an inherent challenge: short probes that provide high
Ruicheng Shi +4 more
semanticscholar +1 more source