Results 211 to 220 of about 5,025 (229)
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PUVA therapy prevents sensitization to mechlorethamine in patients with psoriasis
British Journal of Dermatology, 1985Two groups of 20 patients with psoriasis were treated with mechlorethamine applied topically (group A) or with PUVA combined with mechlorethamine (group B). In group B mechlorethamine was started after six PUVA treatments. Results showed a significant decrease of the incidence of contact dermatitis in group B (30%) compared with group A (75%). Allergic
G Mauduit, J Thivolet, O Silvestre
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Mechlorethamine Hydrochloride Solutions and Ointment
Archives of Dermatology, 1980Solutions of mechlorethamine hydrochloride used to treat patients with mycosis fungoides and psoriasis are stable for many months, especially when they are refrigerated. This fact should make the use of this treatment more convenient. On the other hand, the risk of cancer induction from such use should be appreciated.
Victor Levine +3 more
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Quantum molecular study of the alkylating agent mechlorethamine
International Journal of Quantum Chemistry, 1991Mechlorethamine HN2 is a nitrogen mustard that is recognized as a fundamental model for the alkylating agents belonging to this family. This molecule is an anticancer drug that reacts strongly with intracellular DNA through a complex electrostatic mechanism.
Dane Vasilescu, R. Viani, H. Broch
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33870 Mechlorethamine gel as a maintenance treatment regimen in patients with mycosis fungoides
Journal of American Academy of Dermatology, 2022E. Correia +2 more
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Complete Regressions of Mycosis Fungoides With Topical Mechlorethamine Hydrochloride
JAMA: The Journal of the American Medical Association, 1972Survival of patients with mycosis fungoides, a lymphoma initially appearing in the skin and thereafter spreading to internal organs, has not been substantially improved by chemotherapeutic measures in use over the past two decades. In only a few instances has the disease been reported to undergo complete regression following therapy.
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Respiratory Medicine, 1994
Pleural sclerosis after tube thoracostomy was performed in 40 patients with malignant pleural effusions. The patients were randomly allocated to intrapleural therapy with tetracycline or mechlorethamine. Follow up was obtained on each patient to determine if a symptomatic effusion recurred.
N. Exarchos +3 more
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Pleural sclerosis after tube thoracostomy was performed in 40 patients with malignant pleural effusions. The patients were randomly allocated to intrapleural therapy with tetracycline or mechlorethamine. Follow up was obtained on each patient to determine if a symptomatic effusion recurred.
N. Exarchos +3 more
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Drug Shortage: The Impact of Substituting Mechlorethamine in Stanford V for Hodgkin's Lymphoma
, 2016Introduction: the shortage of some anticancer drugs has forced their substitution in established combination chemotherapy regimens, but the replacement may have critical effects on the results of treatment and need careful evaluation. Since 1996 we treat
Luis P Monteiro +6 more
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Treatment of Inoperable Cancer by Intra-Arterial Administration of Mechlorethamine
A.M.A. Archives of Surgery, 1957This report describes results obtained from the fractionated, regional intra-arterial administration of mechlorethamine hydrochloride (methyl-bis[β-chlorethyl]amine hydrochloride; HN 2 ) in a series of 60 patients with inoperable cancer. In each instance, oxytetracycline (Terramycin) was given concomitantly with the mechlorethamine.
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Cyclophosphamide/Mechlorethamine/Prednisone/Procarbazine/Vincristine
Definitions, 2020semanticscholar +1 more source