Results 91 to 100 of about 21,530 (241)

On the Efficacy and Ecotoxicity of Antifouling Biocides Lethal and Sublethal Effects on Target and Non-target Organisms [PDF]

, 2013
From an environmental perspective, there is a need to reduce the amount of biocides from antifouling paints in the marine ecosystem as these biocides can exert a negative effect on the marine life. One way to do this is to optimize the use of biocides in
Wendt, Ida
core   +1 more source

Analgesic effects of alpha‐2‐adrenoreceptor agonists in equine medicine: systemic, spinal, and local applications

Equine Veterinary Education, EarlyView.
Summary Alpha‐2‐adrenoreceptor agonists provide analgesia when used as sole agents but can also be used in combination with other drugs for their additive and potentially synergistic effects. Further, because of their effects on blood flow, alpha‐2‐adrenoreceptor agonists act to extend and perhaps intensify the effects of drugs, such as local ...
J. Brandly, J. R. Page, J. A. E. Hubbell, W. W. Muir III, K. Hopster   +4 more
wiley   +1 more source

Sedative/Analgesic Efficacy of Medetomidine in Goats [PDF]

Pakistan Veterinary Journal, 2011
Sedative and analgesic efficacy of three intravenous doses of medetomidine, i.e., 4, 5 and 6 µg/kg BW was studied in six goats. A randomized cross over experimental design was used.
Amir Bukhsh Kalhoro* and Abdul Qayoom Memon
doaj  

Classics in Chemical Neuroscience: Medetomidine

ACS Chemical Neuroscience
Medetomidine is an FDA-approved α2-adrenoreceptor (α2-AR) agonist used as a veterinary sedative due to its analgesic, sedative, and anxiolytic properties. While it is marketed for veterinary use as a racemic mixture under the brand name Domitor, the pharmacologically active enantiomer, dexmedetomidine, is approved for sedation and analgesia in the ...
Pedro de Andrade Horn, Tomayo I. Berida, Lauren C. Parr, Jacob L. Bouchard, Navoda Jayakodiarachchi, Daniel C. Schultz, Craig W. Lindsley, Morgan L. Crowley   +7 more
openaire   +2 more sources

Variability in intracellular localization of D‐amino acid oxidase in choroid plexus epithelial cells

The FEBS Journal, EarlyView.
D‐amino acid oxidase (DAO) in choroid plexus epithelial cells (CPECs) shows vesicle‐like localization by histological and super‐resolution analyses. DAO colocalizes with peroxisomal, Golgi, endosomal, lysosomal, autophagosomal, and exosomal markers, indicating diverse subcellular distribution. This suggests DAO is transported within CPECs to metabolize
Koji Ono, Yuji Shishido, Toshiyuki Yamagishi, Kiyoshi Fukui   +3 more
wiley   +1 more source

BOLD-fMRI in the mouse auditory pathway

, 2018
The auditory pathway is widely distributed throughout the brain, and is perhaps one of the most interesting networks in the context of neuroplasticity.
Chavarrias, Cristina, Freches, Guilherme Blazquez, Shemesh, Noam   +2 more
core   +1 more source

Effect of Medetomidine and Combination of Medetomidine/tiletamine/zolazepam and Medetomidine/tiletamine/zolazepam/tramadol on Echocardiographic Cardiac Contractility in Dogs

Journal of Veterinary Clinics, 2015
This study evaluated the myocardial performance on echocardiography after the sedation/anesthesia of medetomidine (D), the combination of medetomidine and tiletamine/zolazepam (DZ), and the combination of medetomidine, tiletamine/zolazepam and tramadol (DZT) in Beagle dogs.
Sang-IL Suh, Tae-Jun Kim, Eun-Chan Lee, Changbaig Hyun   +3 more
openaire   +1 more source

Establishment of an MRI‐Based Diagnostic Approach to Identify Critical Pulpal Inflammation Zones in a Rat Caries‐Derived Pulpitis Model

International Endodontic Journal, EarlyView.
ABSTRACT Aim To establish a magnetic resonance imaging (MRI)‐based diagnostic approach for identifying ‘critical pulpal inflammation’ zones in a rat model of caries‐derived pulpitis. Methodology Caries‐derived pulpitis was induced in the molars of Sprague–Dawley rats using the caries‐derived pulpitis model.
Kiichi Moriyama, Motoki Okamoto, Masakatsu Watanabe, Hailing Huang, Koki Nakatani, Shigeyoshi Saito, Yusuke Takahashi, Mikako Hayashi   +7 more
wiley   +1 more source

Traumatic Occlusion Exacerbates Bone Resorption by Modifying Gene Expression in the Bone Tissue of Ligature‐Induced Periodontitis in Mice

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To clarify the molecular mechanisms of occlusal trauma in bone loss through periodontal tissue transcriptome analysis in mice with periodontitis and traumatic occlusion. Materials and Methods Ligature‐induced periodontitis (Li) and composite resin‐induced traumatic occlusion (Tra) mouse models were established (control [Co], Li, Tra and ...
Yosuke Tsuchiya, Yujin Ohsugi, Tomomitsu Hirota, Yohei Hayashi, Peiya Lin, Yuta Tsukahara, Takanori Iwata, Sayaka Katagiri   +7 more
wiley   +1 more source

A comparative analysis of the effects of Medetomidine and Dexmedetomidine on hemodynamic parameters in cats. Technical note

Revista Científica
Hemodynamic parameters are clinical indicators used in Human and Veterinary Medicine to assess the general health status of patients and identify potential risks.
Eylem Bektaş Bilgiç
doaj   +1 more source