Results 201 to 210 of about 192,651 (303)

The key elements and theoretical logic of the cognitive threshold for participation in winter sports. [PDF]

Sci Rep
Chuo J, Yin Y, Zhang X.
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Unlimited Smartphone Data Plans in Older Adults With Data Deprivation: Quasi-Experimental Study. [PDF]

JMIR Mhealth Uhealth
Choi S, Choi E, Jang SY.
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

A Comprehensive Review of Technological Innovations in Teaching Clinical Nursing Skills: A Scoping Review. [PDF]

Iran J Nurs Midwifery Res
Kamboo MS, Ahmady S, Sohrabi S, Abdollahi H, Hemmatipour A, Mirmoghtadaie Z.   +5 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Integrating SolVES and social media analytics to quantify social value spatial patterns and driving mechanisms in mega-scale green spaces. [PDF]

PLoS One
Fan H, An R, Teng Z, Wang Y.
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

A Cisplatin-Based Prodrug Inhibits Nucleotide Excision Repair Independently of Chromatin Accessibility to Overcome Resistance. [PDF]

Biomolecules
Negev-Korem Y, Golan-Berman H, Heilbrun E, Karmakar S, Soroka Y, Frušić-Zlotkin M, Chen O, Hassanain H, Stern E, Wald O, Gibson D, Kohen R, Adar S.   +12 more
europepmc   +1 more source

Representation in Media Accessibility

This article is a theoretical essay discussing the potential for the analysis of media accessibility contents and practices (AD, SDH, Sign Language Interpreting, etc.) through a queer feminist lens, which makes it possible to tackle the representation of diversity and non-normativity. Based on a literature review of previous workson the intersection of
openaire   +1 more source