Results 71 to 80 of about 1,479,356 (306)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Television Viewing, Satisfaction and Happiness: Facts and Fiction [PDF]
Despite the increasing consumption of new media, watching television remains the most important leisure activity worldwide. Research on audience reactions has demostrated that there are major contradictions between television consumption and the ...
Luca Stanca, Marco Gui
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Trust in various sources of information in war conditions: a sociological analysis of the Ukrainian experience [PDF]
СоціологіяThe war has sharply increased the demand of Ukrainians for news and current information. The situation of active information consumption in wartime has actualized the problem of both the reliability of the information that Ukrainians receive today and ...
Natalia Boyko
doaj +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Eco-nostalgia in Popular Turkish Cinema
, 2015 Book Summary: Ecomedia: Key Issues is a comprehensive textbook introducing the burgeoning field of ecomedia studies to provide an overview of the interface between environmental issues and the media globally.
Monani, Salma, Özdemirci, Ekin Gündüz
core
Semantic Wide and Deep Learning for Detecting Crisis-Information Categories on Social Media [PDF]
, 2017 When crises hit, many flog to social media to share or consume information related to the event. Social media posts during crises tend to provide valuable reports on affected people, donation offers, help requests, advice provision, etc.
F Atefeh +5 more
core +1 more source