Results 51 to 60 of about 17,394,589 (261)

The Impact of Fiscal Councils on Public Perception: A Survey Experiment in the Czech Republic

Financial Internet Quarterly
This study examines the influence of fiscal councils on public opinion regarding fiscal issues. Using a survey-framing experiment on a representative sample of 900 inhabitants of the Czech Republic, the study evaluates how the framing of a message ...
Morda Pavel, Zeman Martin, Klement Josef
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Managing Uncertainty through Fiscal Councils: Communication, Analysis, and Practical Instruments

Business & Management Compass
Background and aim: In the context of economic and political uncertainty, fiscal councils and independent fiscal institutions are playing an increasingly important role in strengthening transparency, accountability, and the democratic governance of ...
Desislava Kalcheva
doaj   +1 more source

Guidelines on parking management : sustainable mobility [PDF]

, 2023
This document is one in a series of documents on Sustainable Mobility and includes other important subjects – Walkability and Accessibility, Shared Transport, Last Mile Transportation and EV Changeover, previously issued by the Local Councils ...
Zammit, Antoine, Local Councils' Association   +1 more
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Le « street art » est-il fini ?

Cahiers de Narratologie, 2016
The polymorphic phenomenon commonly known as « street art » is an evident outcome of the pluralist and post-historical era of art. During the last ten years, it evolved in a way so we can no longer consider it as an isolated practice, characterized by ...
Vittorio Parisi
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Advertising of veterinary medical services on social media

Pubvet
This study presents a literature review based on the Veterinarian’s Code of Ethics, focusing on Chapter XIII – On Advertising and Scientific Works, with the aim of clarifying what is permitted and prohibited regarding veterinarians’ conduct on social ...
Aline Sousa, Shawana Gabriela de Jesus Chagas, Luany Gabrielly Santos Oliveira , Giovanna Bonora Santos, Isabella Caballero Ascani, Marcelo Gomes Figueiredo Filho, Gabriela de Oliveira Chiquinati   +6 more
doaj   +1 more source

The impact of Dutch works councils according to managers [PDF]

Although works councils have, by and large, equally extensive legal rights in Germany and the Netherlands, this is the first econometric analysis that investigates the influence of Dutch works councils on firm performance.
Annette van den Berg, Yolanda Grift, Arjen van Witteloostuijn   +2 more
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source