Results 71 to 80 of about 17,394,589 (261)

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Union of Councils for Soviet Jews, Annual Meeting (Box 56, Folder 26)

open access: yes, 1987
Audio recordings within the Records of Union of Councils for Soviet Jews (I-410) include recordings of interviews with activists, conferences, telephone conversations with Refuseniks and former Prisoners of Conscience, press conferences, Union of ...
Union of Councils for Soviet Jews
core  

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Union of Councils for Soviet Jews, Annual Meeting (Box 56, Folder 39)

open access: yes, 1988
Audio recordings within the Records of Union of Councils for Soviet Jews (I-410) include recordings of interviews with activists, conferences, telephone conversations with Refuseniks and former Prisoners of Conscience, press conferences, Union of ...
Union of Councils for Soviet Jews
core  

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

open access: yesMolecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna   +8 more
wiley   +1 more source

La regulación del mercado alimentario : el caso de la Guadalajara bajomedieval

open access: yesEspacio, Tiempo y Forma. Serie III, Historia Medieval, 2008
El estudio de los mercados medievales es el camino hacia la comprensión de los modernos. La política local y su impacto en el comercio de alimentos son los pilares de un mundo de regulación en el que el espíritu comercial estaba ya despertando ...
José Luis Escribano Abad
doaj   +1 more source

Union of Councils for Soviet Jews Annual Meeting (Box 56, Folder 51)

open access: yes, 1988
Audio recordings within the Records of Union of Councils for Soviet Jews (I-410) include recordings of interviews with activists, conferences, telephone conversations with Refuseniks and former Prisoners of Conscience, press conferences, Union of ...
Union of Councils for Soviet Jews
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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