Results 61 to 70 of about 18,170,611 (288)

Are social embeddedness associated with food risk perception under media coverage?

open access: yesJournal of Integrative Agriculture, 2019
Traceability system has received wide attention in solving food safety issues, via which food information could be tracked back to producer/farmers. Consumers need to obtain this information from producers or social networks, trust in the information ...
Zhen YAN   +3 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Media Coverage & Charitable Giving After the 2004 Tsunami [PDF]

open access: yes
Media coverage of humanitarian crises is widely believed to influence charitable giving, yet this assertion has received little empirical scrutiny. Using Internet donations after the 2004 tsunami as a case study, we show that media coverage of disasters ...
Philip Brown, Jessica Minty
core  

Italy in the Australian news media, 2005-2012 [PDF]

open access: yes, 2013
Presents a systematic analysis of the coverage of Italian matters in the Australian news media in the period 2005-2012. Executive summary The study presents a systematic analysis of the coverage of Italian matters in the Australian news media in the ...
Peter Putnis   +5 more
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Practicing Media—Mediating Practice | Reporting, Uncertainty, and the Orchestrated Fog of War: A Practice-Based Lens for Understanding Global Media Events

open access: yesInternational Journal of Communication, 2020
Media coverage of the ongoing multistate conflict in Syria, extending into Iraq, has been punctuated by the marshaling of conditions for exceptional global media event coverage by states, citizens, and newsmakers alike.
Kenzie Burchell
doaj  

Melbourne’s ‘African Gangs’ and Media Narratives [PDF]

open access: yesSalus Journal, 2019
This paper examines the racialised media coverage of so-called ‘African Gang’ Crime in Melbourne, Australia. It argues that we can usefully examine such media coverage as a risk communication where relevance and authority comes from experiential rather ...
John Gaffey
doaj  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

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