Results 121 to 130 of about 4,306,154 (354)
FEBS Letters, EarlyView.PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley +1 more source
The Democratization of Social Media A Critical Perspective in Technology [PDF]
, 2017 Social Media is part of contemporary technology that is the contentious subject matter within the society. It is paradoxical when social media should provide techniques and objects that serve human being in a positive way, but at the same time, it can ...
Mahaswa, Rangga Kala
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Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Girls and the Media: Girlhood Studies Agenda and Prospects in Italy [PDF]
, 2017 Within the Italian context, girlhood studies can hardly be considered a specific field: adolescence and gender construction in Italy have historically been investigated by sociology and psychology, although, in recent years, media studies have also ...
Romana Ando'
core
Molecular Oncology, EarlyView.Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source
Graphic-Stylistic Expressivity in Media Discourse
SHS Web of Conferences, 2018 The article deals with the analysis of graphic-stylistic means of the language, such as punctuation, functioning in modern English based on the language material of literary and media texts (on-line site of The Guardian).
Ryabova Marina Yu.
doaj +1 more source
, 2004 Locative media uses portable, networked, location aware computing devices for user-led mapping and artistic interventions in which geographical space becomes its canvas.
Hemment, Drew
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Conflicting Climate Change Frames in a Global Field of Media Discourse
, 2016 Reducing global emissions will require a global cosmopolitan culture built from detailed attention to conflicting national climate change frames (interpretations) in media discourse.
Jeffrey P. Broadbent +36 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla +5 more
wiley +1 more source
Meat substitutes in Media Discourse
International Journal of Food StudiesShifting from meat consumption is critical for future dietary evolution. Mainstream newspapers and social media are the leading platforms for expressing this opinion. By analysing the media discourse, the proponents of the shift from meat, to plant-based
Wenxuan Guo
doaj +1 more source