Results 121 to 130 of about 942,723 (307)

Portuguese media discourse on nuclear energy before and after Fukushima: prepared for the EFDA Workprogramme 2012 WP12-SER-ACIF-1 [PDF]

open access: yes, 2013
This report presents the results of the analysis of nuclear related content in Portuguese print media. The report is submitted to the first step of the research task untitled Public Discourse about Nuclear Fusion before and after the Fukushima accident ...
Horta, Ana   +3 more
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Wacana Media Massa Tentang Keikutsertaan Unjuk Rasa Kepala Daerah Menolak Kenaikan Harga Bbm [PDF]

open access: yes, 2012
Government's initiative to r aise fuel price on April 1, 2012 was faced with demonstration in a numberof regions. In fact, local goverenment heads mobilized the people and led a demonstration. Their involvement in the demonstration made the
Karman, K. (Karman)
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Telewizyjny dyskurs polityczny

open access: yesForum Lingwistyczne, 2016
Political Discourse on TV This article describes polish political discourse on TV. The author considers four parameters of discourse’s general organization.
Ewa Szkudlarek-Śmiechowicz
doaj  

Dire le « migrant » dans la ville : une analyse de discours médiatique [PDF]

open access: yesStudii de Lingvistica, 2018
This paper aims at revealing the processes at work in the formation of the political image of the “migrant” in the media. Analysing a corpus of national, regional and local press articles, the idea is to ask: who are we talking about?
Thomas Vetier
doaj  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

I Gotta Testify: Kanye West, Hip Hop, and the Church [PDF]

open access: yes, 2019
The goal of this project, “I Gotta Testify: Kanye West, Hip Hop, and the Church,” is to add a new perspective to the scholarly discourse on Hip Hop and Christianity within classrooms, religious institutions, and popular culture by focusing on Kanye.
Ford, VaNatta S.   +2 more
core   +1 more source

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