Results 41 to 50 of about 1,079,714 (313)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The Photobook Within and As a Heterogeneous Media Environment
, 2022 This proposal suggests that the multiple Artists and Photographs, rather than being an assemblage of photographic art works, constitutes a heterogeneous media environment in which the relationship between the book and photography is renegotiated and put ...
Streitberger, Alexander +1 more
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Disinformation Detection: Developing a Categorical Framework Through Thematic Analysis
Journalism and MediaIn recent years, disinformation has become a significant problem in the media environment. The topic is therefore increasingly relevant in recent research, and authors approach it in different ways. This research aims to provide an answer to the need for
Antea Boko
doaj +1 more source
Family environment, communication and media education
, 2014 The family is the first and most important social group in which are achieved foundations of whole human life. There child acquires his first knowledge, skills and habits. However, upbringing in the family cannot be viewed separated from the wider social
Matilda Karamatic, Brcic, Petani, Rozana
core +1 more source
Developing digital team ethnography of global media events on social media
, 2023 The live character of suddenly breaking global media events along with the massive volume of digital traces they produce pose considerable challenges for research in the current communication environment.
Sumiala, Johanna +3 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source