Results 31 to 40 of about 791,939 (306)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Commentary: The news media – the Prime Minister’s view

open access: yesPacific Journalism Review, 2008
New Zealand has not always been the robust little democracy with the freedom of speech enjoyed today. The election of the first Labour government, the 1951 Waterfront Lockout emergency regulations and the Muldoon era were all testing times for the news ...
Helen Clark
doaj   +1 more source

The Kim Wall Murder Serialized: Ethics & Aesthetics in High-Profile True Crime

open access: yesSeries. International journal of tv serial narratives, 2021
This article investigates the dramaturgical, aesthetical and ethical implications of making television on the back of a high-profile, internationally appealing and very recent murder case: the Kim Wall murder.
Lynge Stegger Gemzøe
doaj   +1 more source

Some challenges for ethics in social network research

open access: yes, 2015
This work was supported by the Engineering and Physical Sciences Research Council [grant numbers EP/J500549/1, EP/M506631/1].Social network sites (SNSes) comprise one of the most popular networked applications of late, with hundreds of millions of users.
Hutton, Luke   +3 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

NOTED: Why so much grimness and so little hope?

open access: yesPacific Journalism Review, 2014
Book review of: The News: A User’s Manual, by Alain de Botton, London: Hamish Hamilton, 2014, 267pp., ISBN9780241146477. The News:Sociologists, ethnographers, political scientists have all focussed their critical faculties on journalism and the news ...
Allison Oosterman, David Robie
doaj   +1 more source

Experiencing Responsibility

open access: yesJournal for Religion, Film and Media, 2022
One central concept in media ethics – and in the field of applied ethics more broadly – is “responsibility”. This contribution asks how the term “responsibility” can be considered productively in the classroom.
Mäder, Marie-Therese
doaj   +1 more source

දිවි තොර කර ගැනීම අපරාධයක් ලෙසින් දැක්විය යුතුද?

open access: yes, 2021
On March 4, 2021 Daily Mirror reported on suicide in a manner that did not comply with media ethics ...
Ethics Eye
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

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