Results 81 to 90 of about 1,719,395 (305)
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Commentary: The news media – the Prime Minister’s view
Pacific Journalism Review, 2008 New Zealand has not always been the robust little democracy with the freedom of speech enjoyed today. The election of the first Labour government, the 1951 Waterfront Lockout emergency regulations and the Muldoon era were all testing times for the news ...
Helen Clark
doaj +1 more source
Plural media ethics? Reformist Islam in India and the limits of global media ethics. [PDF]
Dialect Anthropol, 2021 Kramer M.
europepmc +1 more source
, 2011 As with professional ethics as a whole, media ethics is divided into three parts: metaethics, normative ethics, and descriptive ethics. Metaethics addresses the validity of theories, the nature of good and evil in media programming, the question of universals, problems of relativism, and the rationale for morality in a secular age.
openaire +1 more source
Information sources in Kosovo – traditional media vs. new media [PDF]
, 2014 The information in the digital era has become diverse and redundant. The individual in society gets hundreds and thousands of messages in different ways and channels of communication, but at the end of the day, they remember the most important ones.
Rexhepi, Zija
core
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
NOTED: Why so much grimness and so little hope?
Pacific Journalism Review, 2014 Book review of: The News: A User’s Manual, by Alain de Botton, London: Hamish Hamilton, 2014, 267pp., ISBN9780241146477. The News:Sociologists, ethnographers, political scientists have all focussed their critical faculties on journalism and the news ...
Allison Oosterman, David Robie
doaj +1 more source
Sensitive Coverage Saves Lives: Improving media portrayal of suicidal behaviour [PDF]
, 2007 The report outlines the results of consultations with journalists, suicide prevention agencies and mental health groups conducted by the journalism ethics charity MediaWise.
Cookson, R. +5 more
core
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Purposeful Ephemera: The Implications of Self-Destructing Space Technology for the Future Practice of Archaeology [PDF]
, 2017 This chapter is presented from the perspective of a professional archaeologist who specializes in Greek archaeology, intercultural contact and exchange, and the ethics of cultural heritage.
Justin Walsh
core +1 more source