Results 81 to 90 of about 791,939 (306)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Life under Decree No. 29 of 2010: The Fiji Media Development Decree

open access: yesPacific Journalism Review, 2010
This article examines the domestic and regional impact of a punitive media law introduced in Fiji in June. Decree No. 29 of 2010, the Media Industry Development Decree, is the first of its kind in the South Pacific.
Shailendra Singh
doaj  

CASE STUDY ON MEDIA ETHICS IN FRANCE

open access: yesAnnals of the University of Oradea: Economic Science
Carried out as part of an educational project by Hugo Saez under the supervision of Doina Muresanu, this case study focuses on ethical aspects linked to the field of journalism.
Hugo SAEZ, Doina MURESANU
doaj   +1 more source

REVIEW: Ethics, integrity -but what about truth?

open access: yesPacific Journalism Review, 2000
Review of A fragile freedom: Challenges facing media in Papua New Guinea, edited by Joe Weber. Madang, PNG: Divine World University Press. The booklet has two sections, one briefly devoted to the Divine Word University Media Freedom Day on 30 April ...
David Robie
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

දිවි අහිමි කර ගැනීම් පිළිබඳ වාර්තාකරණය සහ මාධ්‍ය ආචාර ධර්ම

open access: yes, 2021
This entry includes a write-up and infographic. (both in Sinhala)In the month of July 2021 articles published in Aruna and Divaina reported suicides without including helplines while including method of suicide, which violates media ...
Ethics Eye
core   +1 more source

Reporting the Asian tsunami: Ethical issues

open access: yesPacific Journalism Review, 2005
This article explores the ethical issues faced by New Zealand journalists reporting a disaster. Journalists who travelled to Asia to report on the 2004 tsunami were asked to complete an online survey containing a mixture of Likert scale and open-ended ...
James Hollings
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Samoa: The Observer and threats to media freedom

open access: yesPacific Journalism Review, 2010
Commentary: Media freedom is not absolute, which is why we also accept that laws must be instituted, to prevent and discourage media owners, editors and journalists from abusing this freedom.
Savea Sano Malifa
doaj   +1 more source

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