Results 151 to 160 of about 3,154 (260)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Editorial: Advanced EEG analysis techniques for neurological disorders. [PDF]

Front Neuroinform
Jacob JE, Chandrasekharan S.
europepmc   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Pro-Aging: A New Approach to Beauty and Aesthetic Medicine. [PDF]

J Cosmet Dermatol
Fabbri S, Fabbri M.
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

An Open-Source Systematic Reviews Integrated System (OSSYRIS) - Streamlining Processes and Standardising Data Structures. [PDF]

Cochrane Evid Synth Methods
Bosch-Capblanch X, Auer C, Sayem ASM, Deschamps G, Camacho S, Segura L, Al-Aidroos S, Sabblah GT, Wyss K.   +8 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Knowledge and Attitudes Toward Sexual and Reproductive Health Among Adolescents Studying in Government Schools in Tansen Municipality, Palpa, Nepal: A School-Based Cross-Sectional Study. [PDF]

Public Health Chall
Bhattarai S, Poudel S, Sapkota KP, Pokharel R, Adhikari B, Thakurathi B, Rayamajhi RB, Adhikari N.   +7 more
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

The Relationship Between Infertility Stress and Awareness/Utilization of Benefits Under the 'Family and Youth Support Law' Among Iranian Infertile Couples: A Cross-Sectional Study. [PDF]

Health Sci Rep
Azami-Aghdash S, Rezapour R, Rezaeiyeh SB, Sarabi ZV, Najafi L, Nouri M, Ezzati E.   +6 more
europepmc   +1 more source