Results 31 to 40 of about 3,154 (260)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Il lavoro freelance: reputazione e capitale sociale nell’era del “lavoro digitale”

Quaderni di Sociologia, 2015
This article presents the results of a qualitative research on freelance work in the context of the professions of the knowledge economy conducted between 2012 and 2013 across Milan and London.
Alessandro Gandini
doaj   +1 more source

Create to Collaborate: using creative activity and participatory performance in online workshops to build collaborative research relationships

Research Involvement and Engagement, 2023
Background Creative methods/practices have been highlighted as helpful to develop more collaborative, equitable research partnerships between researchers and communities/public-participants.
Alice Malpass, Astrid Breel, Jo Stubbs, Tassos Stevens, Persis-Jadé Maravala, Ellie Shipman, Zoe Banks Gross, Michelle Farr   +7 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

INTERVIEW: Jo Chandler: Gender, human rights and power investigations in Papua New Guinea

Pacific Journalism Review, 2014
INTERVIEW: A series of stories on the complexity and contradictions of Papua New Guinea, Australia’s closest neighbour, has won the 2013 George Munster award for independent journalism.
Jo Chandler, Tom Morton
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Peran Digital Freelancer Marketplace dan Media Sosial Terhadap Perkembangan Gig Economy Worker

Jurnal Pendidikan Ekonomi Undiksha, 2023
The Gig Economy Worker phenomenon is becoming an option for Generation Z to work; the problems that occur are the lack of attention from the Government in providing good guarantees for Gig Economy Workers, so it is necessary to conduct research that has the objective of How to Form Government Attention in Providing Social Security and Protection for ...
Kadek Masakazu Masakazu, null Ersi Sisdianto, null Gede Suwardika, null Dhimas Setyo Nugroho   +3 more
openaire   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Online Allies and Tricky Freelancers: Understanding the Differences in the Role of Social Media in the Campaigns for the Scottish Independence Referendum [PDF]

Political Studies, 2019
Using the 2014 Scottish independence referendum as a case study, this article asks first, to what extent is the use of digital communications technologies, in particular social media, associated with fundamental changes to campaign organizations, specifically to the command and control model?
Langer, Ana Ines, Comerford, Michael, McNulty, Des   +2 more
openaire   +1 more source