Results 211 to 220 of about 66,044 (308)

Designing and implementing a self-learning game with a problem-solving approach to improve students' personal health and healthy nutrition behavior. [PDF]

BMC Res Notes
Ajam Noroozi H, Sharifi N, Joveini H, Rakhshani MH, Alipour Anbrani M.   +4 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Understanding Tourists' Perceptions of Animal Welfare, Governance, and Conservation: Evidence from the Panda Base. [PDF]

Animals (Basel)
Fennell D, Guo Y, Butler R.
europepmc   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Enhancing the role of mass media in the translation of evidence from health policy and systems research in Nigeria. [PDF]

Health Res Policy Syst
Agwu P, Mbachu C, Onwujekwe O.
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

How does the general public perceive hospice and palliative care? -an empirical study from China. [PDF]

BMC Palliat Care
Tang Z, Fan Y, Ye Z, Lu Y, Zhang X, Tang Y, Jing L.   +6 more
europepmc   +1 more source

Destinations of students gaining qualifications from higher education institutions, 2011/12 [PDF]

, 2013
Evans, Siobhan
core  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Excessive screen time and problem behaviours among school-age children in Fujian, China: a cross-sectional study. [PDF]

BMC Public Health
Yu-Ting Y, Li-Xiang C, Miao Y, Yong-Wei Y, Ting L.   +4 more
europepmc   +1 more source