Results 251 to 260 of about 66,044 (308)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Self-Monitoring of Blood Pressure in Yemen: Preliminary Insights Into Knowledge, Attitudes and Practices of Hypertensive Patients. [PDF]

Vasc Health Risk Manag
Al-Quhali AAH, Al-Bassir SS, Abed DS.
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Tourists attitude change in wildlife consumption in and around protected areas in China. [PDF]

One Health
Yang W, He Q, Wang L, Wang Y, Liao W, Ji W, Zhang Y, Chen J.   +7 more
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

How do we engage with the lesbian, gay, bisexual, and transgender community in blood donation and research? Reflections from the Assessing Donor Variability and New Concepts in Eligibility study. [PDF]

Transfusion
Crowder LA, Reik R, Stramer SL, Whitaker BI, Buccheri R, Zurita KG, Gehrig N, Forbes S, Wilson R, Pandey S, Custer B.   +10 more
europepmc   +1 more source

Knowledge, attitudes, and practices of oil and salt intake and related influencing factors in Southwestern China. [PDF]

Front Nutr
Zhang L, Xu Q, Jiang K, Li Z, Wen Y, Hu Z, Xie C, Shi Z, Sharma M, Zhao Y.   +9 more
europepmc   +1 more source

COVID-19 advocacy bias in the <i>BMJ</i>: meta-research evaluation. [PDF]

BMJ Open Qual
Kepp KP, Cristea I, Muka T, Ioannidis JPA.   +3 more
europepmc   +1 more source

Third-child fertility intentions and influencing factors among female workers of reproductive age in Shandong under China's three-child policy. [PDF]

Front Public Health
Qi Y, Wang G, Kuang J, Xu W, Zhang Y, Mu X, Xiao J.   +6 more
europepmc   +1 more source

Construction of a predictive model for cognitive impairment among older adults in Northwest China. [PDF]

Front Aging Neurosci
Wang Y, Wang N, Zhao Y, Wang X, Nie Y, Ding L.   +5 more
europepmc   +1 more source