Results 81 to 90 of about 3,987 (299)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

The Work of Raymond Williams

open access: yestripleC: Communication, Capitalism & Critique, 2014
This podcast is a recording of Jim McGuigan's talk "The Work of Raymond Williams" that he presented in the CAMRI Research Seminar at the University of Westminster on October 15, 2014.
Jim McGuigan
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Analysis of organizational and managerial structure on the case of Serbian film association [PDF]

open access: yesEkonomija: teorija i praksa, 2015
Serbian Film Commission (with the brand name - FilminSerbia) is the first film association in Serbia, which operates as an independent, nonprofit, professional association.
Simić Vladimir
doaj  

Tradução e adaptação cultural do Questionário Aberdeen para Veias Varicosas Translation and cultural adaptation of Aberdeen Varicose Veins Questionnaire

open access: yesJornal Vascular Brasileiro, 2012
CONTEXTO: Atualmente há um crescente interesse por instrumentos de avaliação em saúde produzidos e validados em todo o mundo. Apesar disso, ainda não temos no Brasil instrumentos que avaliem o impacto da doença venosa crônica na vida de seu portador ...
Flávia de Jesus Leal   +6 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

2000 -luvun haasteita: miten freelancerit sitoutetaan? Tutkimuksen kohteena Suomen media alalla työskentelevät freelance journalistit

open access: yes, 2020
Freelancing has become popular all across the globe. This increased interest in freelancing has traditionally been explained by the changing world of work, and the occurring change of generations.
Lyytikäinen, Salla
core  

Fansubbing de l'espanyol al xinès : organització, rols i normes en l'escriptura col·laborativa

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2016
Objectiu: documentar i analitzar la cooperació en línia d'una comunitat digital que subtitula sèries i pel·lícules hispanes al xinès; estudiar-ne els rols i les funcions, la cadena de treball, els espais virtuals, les estratègies d'autoregulació i les ...
Zhang, Tian Leticia, Cassany, Daniel
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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