Results 91 to 100 of about 2,807,409 (305)
Valokeilassa Kauneus & Terveys -lehden avustavien toimittajien yhteistyö toimeksiantajan kanssa [PDF]
, 2017 Työn toimeksiantaja on Kauneus & Terveys, joka on vuodesta 1956 ilmestynyt hyvinvointiin keskittyvä naisille suunnattu aikakauslehti. Opinnäytetyöni tarkoitus on kartoittaa Kauneus ja Terveys -lehden vakituisten toimittaja-avustajien kokemuksia ...
Savolainen, Nora
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Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
China Employment Law Update - August 2017 [PDF]
, 2017 In This Issue: Guangdong Province High Court Provides Guidance on Labor Disputes Shanghai Second Intermediate Court Issues Employment Dispute White Paper for 2013–2016 Transgender Employee Wins Compensation For Unlawful Termination and Infringement of ...
Baker & McKenzie
core +1 more source
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
From commercial marketing to electoral marketing: candidates’ attributes in the perception of Brazilian and American voters [PDF]
, 2017 This study investigates attributes that influence the vote in different socioeconomic contexts (Brazil/USA). Our results show an asymmetric effect of candidates’ attributes on voters’ decision.
Mainardes, Emerson +3 more
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Domination and the Arts of Digital Resistance in Social Media Creator Labor
Social Media + SocietyThis article conducts a collaborative qualitative thematic analysis of in-depth interviews with social media content creators (N = 53) based in and/or originated from the United Kingdom.
Errol Salamon, Rebecca Saunders
semanticscholar +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Agile values and their implementation in practice [PDF]
, 2015 Today agile approaches are often used for the development of digital products. Since their development in the 90s, Agile Methodologies, such as Scrum and Extreme Programming, have evolved.
Escalona Cuaresma, María José +2 more
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A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source