Results 31 to 40 of about 19,234,587 (316)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Youthworx media: youth media and social enterprise as intervention and innovation [PDF]
, 2013 This research explores the impact of Youthworx, a community-based cross-sector response to the problem of youth marginalisation and social exclusion. Preface Youthworx is a successful model of a practical, community-based, cross-sector response to the ...
Aneta Podkalicka +6 more
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Media and Communication, 2019 This study synthesises two analytical frameworks—journalistic strangers and agents of media innovation—to examine how perceptions among newsworkers towards new entrants to their field shape the normalisation of innovations in a digital-first legacy news ...
Sherwin Chua, Andrew Duffy
doaj +1 more source
Media Innovation and Social Change: Introduction to the Special Issue
The Journal of Media Innovations, 2020 Our purpose with this Special Issue is to present and contribute to a body of research that critically explores the relationship between media innovation and social change. In doing so, we also outline the contours of a research agenda to further develop this emerging field. Our motivation arises from a review of research published in the nine previous
Ni Bhroin, Niamh, Milan, Stefania
openaire +5 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
A Comprehensive Study on Pathfinding Techniques for Robotics and Video Games
International Journal of Computer Games Technology, 2015 This survey provides an overview of popular pathfinding algorithms and techniques based on graph generation problems. We focus on recent developments and improvements in existing techniques and examine their impact on robotics and the video games ...
Zeyad Abd Algfoor +2 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
, 2013 In order to understand and explain current developments in the media landscape, using the lens of innovation and innovation theory adds value to media research. This chapter gives a theoretical introduction to the concept of innovation. It argues that media innovations may be related to product innovation, process innovation, position innovation ...
Storsul, Tanja, Krumsvik, Arne H.
openaire +3 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source