Results 41 to 50 of about 19,234,587 (316)

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Social Media and Innovations : Case Studies in Automotive Industry

open access: yes, 2023
The integration of social media platforms into our daily lives has not only revolutionized communication and connected people from diverse backgrounds but has also emerged as a powerful tool for businesses to innovate and maintain their competitive edge.
openaire   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

“It’s New to Us”: Exploring Authentic Innovation in Local News Settings

open access: yesMedia and Communication
Many local newsrooms across the globe have been forced to re-assess (and re-assert) their value and function during a period of intense digital disruption.
Ragnhild Kr. Olsen, Kristy Hess
doaj   +1 more source

Stimulating Brand Innovation Strategy via Knowledge Acquisition, Market Orientation, and Strategic Capability Using Social Media Within China’s Online Technology Industry

open access: yesFrontiers in Psychology, 2022
In the context of China’s online technology business, this study explores the linkages between knowledge acquisition via social media, two modes of market orientation (proactive and responsive), social media strategic capability, and brand innovation ...
Yaliu Yang, Xiaowei Zheng, Xiaowei Zheng
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Media-Tech Companies as Agents of Innovation: From Radical to Incremental Innovation in a Cluster

open access: yesMedia and Communication
During recent decades new players, forms, and practices have been entering the journalism field, prompting a re-examination of journalism’s professional and organizational boundaries.
Ana Milojevic, Leif Ove Larsen
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Research on the effect of image size on real-time performance of robot vision positioning

open access: yesEURASIP Journal on Image and Video Processing, 2018
In order to improve the real-time performance of visual positioning of the indoor mobile robot, the researchers found that the shape and size of the positioned image have a great influence on the real-time performance of the positioning calculation.
Desheng Lyu, Heyang Xia, Chen Wang
doaj   +1 more source

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