Results 61 to 70 of about 2,042 (215)
Communications EngineeringUltrasound imaging requires users to infer three-dimensional anatomy from two-dimensional slices, imposing steep training demands that limit broader adoption.
Jason F. Hou +5 more
doaj +1 more source
Closed-loop functional optogenetic stimulation
Nature Communications, 2018 Optogenetics is a promising alternative approach for restoration of neuromuscular function. Here the authors establish a closed-loop functional optogenetic stimulation for the control of limb joint angle in murine models, which demonstrates improved ...
Shriya S. Srinivasan +4 more
doaj +1 more source
Behavioral attributes and financial churn prediction
EPJ Data Science, 2018 Customer retention is crucial in a variety of businesses as acquiring new customers is often more costly than keeping the current ones. As a consequence, churn prediction has attracted great attention from both the business and academic worlds ...
Erdem Kaya +5 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
A framework for handweaving robotic textiles with liquid crystal elastomer fibers
Scientific ReportsTextile production methods present a rich set of strategies for developing materials with both form and function encoded at the fiber scale. Beyond simply acting as a static flexible barrier, the ability to incorporate environmentally responsible ...
Sarah Nicita +3 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Light-induced rolling of azobenzene polymer thin films for wrapping subcellular neuronal structures
Communications ChemistryNeurons are essential cells composing our nervous system and orchestrating our body, thoughts, and emotions. Recently, research efforts have been focused on studying not only their collective structure and functions but also the single-cell properties as
Marta J. I. Airaghi Leccardi +5 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
A Dynamic Ultrasound Phantom with Tissue‐Mimicking Mechanical and Acoustic Properties
Advanced ScienceTissue‐mimicking phantoms are valuable tools that aid in improving the equipment and training available to medical professionals. However, current phantoms possess limited utility due to their inability to precisely simulate multiple physical properties ...
Sara V. Fernandez +7 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source