Results 41 to 50 of about 116,127 (264)

Pirin Transcriptionally Regulates PLA2G4A To Inhibit Ferroptosis in Colorectal Cancer via Lipid Profile Remodeling

Advanced Science, EarlyView.
This study identifies Pirin (PIR), an iron‐binding protein, as a critical ferroptosis suppressor in colorectal cancer through lipid membrane remodeling. PIR, induced by NRF2 during ferroptotic stress, transcriptionally regulates PLA2G4A to shift cellular lipid composition away from ferroptosis‐permissive polyunsaturated phospholipids.
Wei Shi, Yue Qi Ong, Prativa Majee, Esther SM Wong, Amhed Missael Vargas Velazquez, Kerem Fidan, Pierce Kah‐Hoe Chow, Wai Leong Tam, Ker Kan Tan, Iain Beehuat Tan, Vinay Tergaonkar   +10 more
wiley   +1 more source

A Wireless, Battery‐Free Artificial Throat Patch with Deep Learning for Emotional Speech Recognition

Advanced Science, EarlyView.
In this work, Xu and co‐workers develop a wireless, battery‐free artificial throat patch system (ATPS) consisting of a carbon nanotube‐based thin‐film strain sensor and a miniaturized flexible printed circuit board, to enable real‐time sensing of throat signals.
Bingxin Xu, Guanming Lin, Xiaohui Hong, Chuting Liu, Xinyi Qu, Kangjian Jiao, Lei Zhang, Bingzhe Xu, Jun Yan, Yancong Qiao, Xudong Lin   +10 more
wiley   +1 more source

Evaluating ESL classroom evaluation: teacher–student beliefs and teacher practices in Sunyani East Municipality, Ghana

Discover Education
Given the important role of evaluation in the language-learning classroom, understanding its application in a particular context is crucial for improving language learning outcomes.
Gorden Naandung Feikaab, Francis Bukari, Emmanuel Lauren Oblie   +2 more
doaj   +1 more source

Media Linguistics or Linguistic Media Studies? Some Comments about Relationships and Opportunities for Research in the Field of Linguistics and Media Science

Perspectives on Culture, 2022
Celem artykułu jest określenie współczesnych związków lingwistyki, w tym zwłaszcza lingwistyki stosowanej, z medioznawstwem. Autorzy wskazali obszary przenikania się obydwu dyscyplin oraz ich subdyscyplin, ukazując możliwości współpracy lingwistów i medioznawców, w tym współpracy o naturze interdyscyplinarnej.
Laskowska, Małgorzata, Marcyński, Krzysztof, Szerszeń, Paweł   +2 more
openaire   +1 more source

Mechanical Overloading‐Induced Nanomineral Crystal Perturbation from the Osteochondral Interface: A Potential Initiator of Osteoarthritis

Advanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Nan Jiang, Rong Ren, Zhan Su, Jiahao Zhou, Pinyin Cao, Sicheng Zhang, Zhen Li, Chao Li, Songsong Zhu   +8 more
wiley   +1 more source

University Media Discourse as a Means of Patriotic Education for Young People

Виртуальная коммуникация и социальные сети, 2023
Most institutions of higher education have official websites that are represented in social networks and messengers, thus providing students with relevant information.
Natalia S. Olizko
doaj   +1 more source

Targeted Degradation of eEF2K by a Structure‐Guided PROTAC Strategy for the Treatment of Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study developed an eEF2K‐targeting PROTAC, A6, that efficiently degrades eEF2K in TNBC cells, inhibiting tumor growth in vitro and in vivo. To enhance tumor‐specific delivery, we engineered A6@ZIF‐8, a pH‐sensitive nanocarrier, which improved drug accumulation at tumor sites, offering a promising therapeutic strategy for TNBC through targeted ...
Shijun Cao, Changxin Zhong, Shilong Jiang, Yungui Li, Yang Xi, Mingxuan Xiao, Ting Jiang, Xiaoya Wan, Zonglin Chen, Xiaohui Yu, Yan Cheng   +10 more
wiley   +1 more source

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

Advanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling, Aïda Yakhlef Sanchez, Nicolas Thelen, Müge Senarisoy, Maria Hogg, Steven Condamine, Andrea Lelli, Emilia Wysocka, Pranav Patni, Sandrine Vitry, Kerem Yasin Yildizhan, Sébastien Le Gal, Sylvie Nouaille, Michael R. Bowl, Marc Thiry, Didier Dulon, Sedigheh Delmaghani, Aziz El‐Amraoui   +17 more
wiley   +1 more source

 Landscape of inscriptions on commercial vehicles in a Ghanaian city

Discover Cities
Linguistic landscapes (LL) serve as important media for expressing identity, cultural heritage and societal values within urban spaces. This study explores the linguistic inscriptions on commercial intra-city vehicles in the Sekondi-Takoradi Metropolis ...
Ramos Asafo-Adjei, Francis Bukari, Ernest Kwesi Klu   +2 more
doaj   +1 more source

How Perceived Motivations Influence User Stickiness and Sustainable Engagement with AI-Powered Chatbots—Unveiling the Pivotal Function of User Attitude

Journal of Theoretical and Applied Electronic Commerce Research
Artificial intelligence (AI) is reshaping customer service, with AI-powered chatbots serving as a critical component in delivering continuous support across sales, marketing, and service domains, thereby enhancing operational efficiency.
Hua Pang, Zhuyun Hu, Lei Wang
doaj   +1 more source