Results 31 to 40 of about 888,008 (218)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Efektifitas Media Online yang digunakan dalam Proses Pembelajaran Daring

open access: yesPalapa: Jurnal Studi Keislaman dan Ilmu Pendidikan, 2021
The covid-19 pandemic era forced teachers and educators to apply learning by applying online models. Many platforms are offered to facilitate learning, of course it confuses what application is suitable to use so that learning continues to run well even ...
Aziz Kurniawan
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Advertising Special Project in Online Media: Characteristics of Phenomenon in Russian Research

open access: yesНаучный диалог, 2022
A review of Russian studies, which are devoted to the study of the content and structural features of advertising special projects, is made. This phenomenon is at the intersection of multimedia journalism, digital marketing and Public Relations.
K. A. Boldina
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Analisis Wacana Kritis terhadap Pemberitaan Akun Fufufafa di Media Tempo.co

open access: yesJurnal Ilmu Sosial dan Ilmu Politik
The reporting of the “Fufufafa” account, which allegedly belongs to Gibran Rakabuming Raka, has become a viral issue on social media X and has received national attention. The news can shape public opinion among the community.
Arya Eka Rahadi, Didi Permadi, Sarwo Edy
doaj   +1 more source

Online Media Ethics and the Privacy of Politicians in Kosovo

open access: yesInformacijos Mokslai, 2018
[full article and abstract in English] The pluralism of online media outlets, as well as the objective of these outlets to be the first to inform on events, may possibly lead these outlets to disrespect professional ethics. This paper will discuss the
Muhamet Jahiri, Dren Gërguri
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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