Results 41 to 50 of about 888,008 (218)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Analisis Framing Pemberitaan Program Kerja Makan Siang Gratis Prabowo-Gibran Dalam Media Online Liputan6.Com Dan Republika.co.id

open access: yesJurnal Ilmu Sosial dan Ilmu Politik
The 2024 presidential election is becoming an important moment in the political landscape of Indonesia. Where Prabowo Subianto and Gibran Rakabuming Raka successfully won the majority of votes.
Fadisa Rahma Devi Triana   +1 more
doaj   +1 more source

PENYELESAIAN SENGKETA BISNIS MELALUI ONLINE DISPUTE RESOLUTION DAN PEMBERLAKUANNYA DI INDONESIA

open access: yesMimbar Hukum, 2008
This paper is an attempt to discuss some issues concerning of business settlement via Online Dispute Resolution (ODR), Online Arbitrate Agreement, Online Arbitrate Procedure, Online Arbitrate Judgment, and examining the practice of the ODR in Indonesia ...
Bambang Sutiyoso
doaj  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

News Media Credibility comparative between Internet and Television in Jordan [PDF]

open access: yesالمجلة المصرية لبحوث الإعلام, 2018
In this study, a survey design was used to determine the factors influences the perception of media credibility in Jordanian societies to decipher how respondents perceive the Internet and television in terms of credibility for news information. A survey
Maged El Khodary
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

The Development of Online Learning Media by Using Moodle for General Chemistry Subject

open access: yesJournal of EST (Educational Science And Technology), 2020
This study aims to develop and obtain eligible online learning media by using moodle for general chemistry subjects by using moodle. In this study, flash animation and simulation were integrated as online media in moodle to attract students’ motivation ...
Asyti Febliza, Oktariani Okatariani
doaj   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli   +5 more
wiley   +1 more source

Strategi Media Online Lensatimur dalam Mengangkat Kearifan Lokal (Studi Kasus Pariwisata Indonesia Timur)

open access: yesExpose, 2019
Abstrak. Penelitian ini bertujuan untuk mengetahui strategi media online Lensatimur pada website dan konten yang dibuat, mengetahui mekanisme kerja Lensatimur, dan kendala yang terjadi pada produksi.
Noviawan Rasyid Ohorella
doaj   +1 more source

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