Results 111 to 120 of about 2,227,215 (313)

Effect of the nitrogen source on glutamine and alanine biosynthesis in Neurospora crassa. An in vivo 15N nuclear magnetic resonance study [PDF]

open access: yes, 1982
The influences of different nitrogen sources on the relative rates of biosynthesis of glutamine and alanine have been studied by 15N nuclear magnetic resonance spectroscopy of intact Neurospora crassa mycelia suspensions.
Kanamori, Keiko   +3 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Media in the digital age: Regulatory aspects [PDF]

open access: yesZbornik Radova Pravnog Fakulteta u Nišu, 2019
The huge impact of digital technology has led to reconsidering the concept of the media. In theory, there is a common agreement about the new concept of the media, offered by Karol Jakubowicz (2009), which includes new content forms, new creators of ...
Mihajlov-Prokopović Anka   +1 more
doaj  

A Call for Change: The Evolution of the Modern Documentary from Informative Media to Persuasive Platform [PDF]

open access: yes, 2011
In the past several years, new documentaries have begun to evolve from informative media to persuasive platform as a result of changing cultural contexts and ideologies.
England, Valerie
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Media in War: An Overview of the European Restrictions on Russian Media

open access: yesEuropean Papers
(Series Information) European Papers - A Journal on Law and Integration, 2023 8(3), 1235-1245 | European Forum Insight of 24 January 2024 | (Table of Contents) I.
Gergely Ferenc Lendvai
doaj   +1 more source

The Media Activism of Latin America’s Leftist Governments: Does Ideology Matter? [PDF]

open access: yes
Has Latin America’s left turn mattered in media politics? Does ideology impact governments’ practices and policies regarding media and journalistic institutions?
Philip Kitzberger
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

CHALLENGES TO FREEDOM OF SPEECH AND SAFETY OF JOURNALISM IN UKRAINE

open access: yesІнтегровані комунікації
This study evaluates the dangers and challenges faced by journalists in Ukraine during Russia's full-scale war against the country. The war and the imposition of martial law aimed at ensuring national security have restricted the operational capabilities
Galyna Piskorska
doaj   +1 more source

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