Results 101 to 110 of about 2,227,215 (313)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Between public health and commercial pressure: health communication and media oversight in Indonesia local radio

open access: yesFrontiers in Communication
This study investigates the proliferation of herbal medicine advertising on local radio stations in West Java, Indonesia, with attention to regulatory gaps, media ethics, and public health risks.
Muhammad Sufyan Abdurrahman   +4 more
doaj   +1 more source

Tackling the spread of disinformation Why a co-regulatory approach is the right way forward for the EU. Bertelsmann Stiftung Policy Paper 12 December 2019 [PDF]

open access: yes, 2019
In recent years social media platforms have led to an unprecedented increase in the spread of disinformation. Concerns about these new and dynamic ways to spread falsehoods have brought politicians and regulators onto the stage. In this paper Paul-Jasper
Dittrich, Paul-Jasper
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

NZ watchdogs must keep up with media’s changing face

open access: yesPacific Journalism Review, 2012
A discussion paper released by the New Zealand Law Commission just before the end of 2011 looked into how well the regulatory framework governing the NZ media was working, and concluded that change was needed.
Linda Clark
doaj   +1 more source

How to Regulate (and Not Regulate) Social Media

open access: yesSSRN Electronic Journal, 2019
"To understand how to regulate social media, you have to understand why you want to regulate it. I will say something about specific regulatory proposals in the last part of this essay. But I want to spend most of my time discussing the why as much as the how.
openaire   +3 more sources

Media regulation and democracy [PDF]

open access: yesIndex on Censorship, 1994
Contrary to the general view, regulation can be the defender of free speech and the forces of the marketplace the chief threat to a plurality of view. But new technologies demand new forms of regulation and government intervention may be the best way of ensuring the plurality of voice on which democracy depends
openaire   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Peranan Self Regulation Di Tengah Konstelasi Industri Media Pada Harian Republika

open access: yesKomunikator, 2018
Regulation and Journalistic Code of Ethic plays an important role as a guide for professional journalists. Similarly, self-regulation that plays an important role as Principles, Code of Ethics, and Standards of Conduct for the press and media companies ...
Rizki Tania   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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