Results 101 to 110 of about 30,781,799 (291)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Decentering Media Studies, Verbing the Audience: Methodological Considerations Concerning People’s Uses of Media in Urban Space [PDF]

open access: yes, 2016
Media studies scholars are invited today to address the pervasive mediation of contemporary cities, together with researchers from human geography, urban studies, science and technology studies, and mobility studies.
Tosoni, Simone, Ridell, Seija
core  

Modern Blogging Media Space

open access: yes, 2022
Media space is an electronic environment in which individuals or their groups and other communities can act together simultaneously. In this space, they can create a visual and sound environment that affects the actual, real space.
Humeniuk Tetiana   +1 more
core   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Space Organizations

open access: yes, 2005
presentrollgraphPresentationrollGraphInteractive Media ElementThis interactive chart shows the organizations that use the DoD space systems, their relationships, and their functions.SS3011Space Systems Technology and ...

core  

Media as Democratic Public Space? [PDF]

open access: yes, 2020
Media as Democratic Public Space? – This paper explores the potential of the present-day traditional and new media to establish an “open space” of action, deliberation and political participation of democratic citizens.
Mašek, Vojtěch
core   +1 more source

06361 Abstracts Collection – Computing Media Languages for Space-Oriented Computation [PDF]

open access: yes, 2007
From 03.09.06 to 08.09.06, the Dagstuhl Seminar 06361 ``Computing Media and Languages for Space-Oriented Computation'' was held in the International Conference and Research Center (IBFI), Schloss Dagstuhl.
DeHon, André   +2 more
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Recursive space: play and creating space [PDF]

open access: yes, 2012
Space is reconfigured through the participations of both gamers and the game, where game is understood as the programming and hardware of a game technology.
Aylish Wood, Wood, Aylish
core   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

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