Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Emerging Methods and Challenges Associated With Teaching and Learning Media Studies During the COVID-19 Pandemic Induced Lockdowns in Zimbabwe and South Africa. [PDF]
Sage Open, 2023 Chibuwe A, Munoriyarwa A.
europepmc +1 more source
Ultra-Slow Light and Enhanced Nonlinear Optical Effects in a Coherently Driven Hot Atomic Gas
, 1999 We report the observation of small group velocities of order 90 meters per second, and large group delays of greater than 0.26 ms, in an optically dense hot rubidium gas (~360 K).
A. Imamoğlu +23 more
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
International Journal of Communication, 2017 Drawing on the affect infusion model and on affective disposition theory, this study aims to explain the influence of viewers’ affective disposition toward the guests of political TV talk shows on their information processing and judgments.
Carina Weinmann +6 more
doaj +2 more sources
Big AI: Cloud infrastructure dependence and the industrialisation of artificial intelligence
Big Data & SocietyCritical scholars contend that ‘There is no AI without Big Tech’. This study delves into the substantial role played by major technology conglomerates, including Amazon, Microsoft, and Google (Alphabet), in the ‘industrialisation of artificial ...
Fernando van der Vlist +2 more
doaj +1 more source
Case Study on Detecting COVID-19 Health-Related Misinformation in Social Media [PDF]
, 2021 Mir Mehedi Ahsan Pritom +6 more
openalex +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The Effects of Social Media Use on the Perceptions of Mental Illness Among College Students [PDF]
, 2019 This study examined individuals’ use of and perceptions of social media networking sites (i.e. Facebook and Twitter) on their perceptions of mental illness.
Fisher, Brea
core +1 more source
An analysis of UK Policing Engagement via Social Media [PDF]
, 2017 Police forces in the UK make use of social media to communicate and engage with the public. However, while guidance reports claim that social media can enhance the accessibility of policing organisations, research studies have shown that exchanges ...
Alani, Harith +2 more
core +1 more source