Results 121 to 130 of about 2,599,820 (309)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
ENGLISH- STEREOTYPING OF ISLAM AND MUSLIMS IN HOLLYWOOD MOVIES: AN ANALYSIS OF REPRESENTATION
دی اسکالر, 2020 Hollywood movies are very popular in most nations around the world and the viewers of these countries turn to Hollywood blockbusters for entertainment purposes.
Muhammad Yousaf +3 more
doaj
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
What Makes the Headlines: A Five-Year Analysis of the Front Page of the 'Ghanaian Times'
Journal of Arts, Humanities and Social ScienceThis study aimed to identify the various story types featured on the front pages of the ‘Ghanaian Times’ newspaper. Utilising the gatekeeping and framing theories, the study aimed to establish the dominant story types, news actors, and story settings ...
Kwaku Baah-Acheamfour +1 more
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
, 2012 The authors discuss the concept of intermediality for research in early cinema. After a general introduction to intermediality as research problem in media studies, the question is raised whether the concept of intermediality can be used in diachronic ...
de Zwaan, Klaas +8 more
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
PLENARY SESSION IV. Rhetorics in Media Studies – Media Studies in Rhetorics. Rhetoric in Media Studies [PDF]
Nordicom Review, 2004 openaire +3 more sources
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source