Results 141 to 150 of about 2,599,820 (309)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Foundations of Applied Media Studies
, 2018 Each of the collaboratively authored chapters of Applied Media Studies was produced through a series of interview-style questions that I, as editor, developed and circulated to the contributors.
Losh, Elizabeth +8 more
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Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
The Paradox of Liveness. From the Broadcast Media Era to the Social Media Era
, 2014 Liveness has been a persistent and much-debated concept in media studies. It has long been associated with broadcast media, and television in particular.
van Es, K.F. +2 more
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Global Media and Communication : Vol.11, No.1, April 2015
, 2015 1. A community of communities ? emerging dynamics in the community media paradigm / Christopher Ali, David Conrad 2. Sectarianism and the arab spring : Framing the popular protests in bahrain / Ahmed K Al-Rawi 3. Transnationalization of Turkish dramas :
Department of Media Studies
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Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Media Tactics in the Long Twentieth Century
Integrating media studies with history, Media Tactics in the Long Twentieth Century explores the dynamic relationship between tactics and strategies in recent history. Drawing on examples from a range of different countries and world regions, and looking
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Reactionary sensemaking: Mapping the micropolitics of online oppositional subcultures
Big Data & SocietyInternet memes used to be funny, but somewhere in the mid-2010's, a darker dimension surfaced. This editorial explores this ‘reactionary turn’ in digital culture through a collection of articles and commentaries on ‘the micropolitics of online ...
Marc Tuters +4 more
doaj +1 more source