Results 131 to 140 of about 31,242,454 (306)

The pupil in the text : rhetorical devices in classroom teaching films of the 1940s, 1950s and early 1960s [PDF]

open access: yes, 2010
Since the late 1990s, there has been a marked increase in academic interest in what are sometimes referred to as ‘utility films’: audio-visual texts intended not so much for the entertainment of an audience, but rather to inform it, train it or teach it ...
Media Studies   +2 more
core   +1 more source

What Makes the Headlines: A Five-Year Analysis of the Front Page of the 'Ghanaian Times'

open access: yesJournal of Arts, Humanities and Social Science
This study aimed to identify the various story types featured on the front pages of the ‘Ghanaian Times’ newspaper. Utilising the gatekeeping and framing theories, the study aimed to establish the dominant story types, news actors, and story settings ...
Kwaku Baah-Acheamfour   +1 more
doaj   +1 more source

To Media Study: Media Studies and Beyond

open access: yesThe Journal of Media Art Study and Theory, 2020
openaire   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Media studies to enhance the production of verticillins facilitated by in situ chemical analysis. [PDF]

open access: yesJ Ind Microbiol Biotechnol, 2018
Amrine CSM   +4 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Beelden van tijd : Op zoek naar de tijdsdramaturgie in de Proustcyclus van Guy Cassiers [PDF]

open access: yes, 2009
Not only does theatre reflect our contemporary mediatized society, but theatre makers increasingly employ (digital) media in their performances that inspire and challenge them to explore new forms of making, showing and telling.
Media Studies   +2 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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