Results 221 to 230 of about 48,502,445 (376)

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

Media Studies 2.0: A Retrospective [PDF]

open access: yes, 2011
Berger, Richard, McDougall, Julian
core  

Residency Rewired: An Analysis of Otolaryngology Residency Programs on Websites and Social Media. [PDF]

open access: yesLaryngoscope Investig Otolaryngol
Clark DES   +4 more
europepmc   +1 more source

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

open access: yesMolecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza   +5 more
wiley   +1 more source

A Narrative Review of Nicotine and Alcohol Addiction Recovery Content on TikTok. [PDF]

open access: yesJ Korean Acad Child Adolesc Psychiatry
McCurdy LY, Na PJ, Potenza MN.
europepmc   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy