Results 21 to 30 of about 5,585,373 (243)
Comedic affordances in digital game soundscapes [PDF]
, 2014 Among audiovisual media, the peculiar aspect of digital games is in the nontrivial effort required from the user to traverse them (Aarseth, 1997).
Oliva, Costantino +1 more
core
The Purpose of Black Role Models [PDF]
, 2021 When thinking of role models, the notion is typically speculated from the perspective of the youth; though, black role models are known to have a direct contribution on the lives of men and women in all stages of adulthood as well (18+).
Williams, Chris
core +1 more source
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
The Impact of Social Isolation during the COVID-19 Pandemic: A Personal Account of Social Isolation [PDF]
, 2022 I am no stranger to social isolation and its effects on my mental, emotional and physical health. A variety of factors such as limited research, misconceptions associated with its impact mainly in older adults, and its interchangeability with loneliness,
Espinal Ramos, Patricia
core +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
FEBS Letters, EarlyView.In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti +3 more
wiley +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
miRNA‐29 regulates epidermal and mesenchymal functions in skin repair
FEBS Letters, EarlyView.miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan +10 more
wiley +1 more source
Ecological Studies on Nepenthes at Barito Ulu, Central Kalimantan, Indonesia [PDF]
, 2008 Ecological studies on the Nepenthes species at Barito Ulu, Central Kalimantan, Indonesia were conducted between August 2005 and September 2006. Surveys and two small plot inventories were used to determine the diversity and population of Nepenthes at the
Mansur, M. (Muhammad)
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Alien nation: contemporary art and black Britain [PDF]
, 2011 About the book: This fascinating text introduces readers to postcolonial theory using the context of British media culture in ethnic minority communities to explain key ideas and debates.
Wainwright, Leon
core +1 more source