Results 41 to 50 of about 2,319,665 (294)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Manipulative Technologies in the Information Wars: The experience of Post-Soviet journalism

Інтегровані комунікації, 2021
This is the article researching the manipulation of the post-Soviet media from the analytics and social cultural viewpoint. Moreover, it establishes principle criteria of manipulation efficiency and elucidates, its status and characteristics of the ...
Iryna Ivanova, Kateryna Yaresko
doaj   +1 more source

Exploiting Text and Network Context for Geolocation of Social Media Users

, 2015
Research on automatically geolocating social media users has conventionally been based on the text content of posts from a given user or the social network of the user, with very little crossover between the two, and no bench-marking of the two ...
Baldwin, Timothy, Cohn, Trevor, Rahimi, Afshin, Vu, Duy   +3 more
core   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

ON THE ISSUE ABOUT THE EFFECTIVENESS OF NARRATIVE ADVERTISING IN POPULAR SCIENCE JOURNALS

Вестник университета, 2020
The issue of studying the effectiveness of advertising in popular science journals does not occupy a large place in scientific research. This state of affairs is challenging, since the activities of popular science journals are aimed at attracting the ...
E. V. Shcherbakova, D. M. Belugina, E. V. Zvonova   +2 more
doaj   +1 more source

AXES at TRECVid 2011 [PDF]

, 2011
The AXES project participated in the interactive known-item search task (KIS) and the interactive instance search task (INS) for TRECVid 2011. We used the same system architecture and a nearly identical user interface for both the KIS and INS tasks. Both
Aly, Robin, Arandjelovic, Relja, Beunders, Henri, Chen, Shu, Frappier, Mathieu, Jawahar, C. V., Juneja, Mayank, Lee, Hyowon, Martijn, Kleppe, McGuinness, Kevin, O'Connor, Noel E., Ordelman, Roeland, Schneider, Daniel, Schwenninger, Jochen, Smeaton, Alan F., Tschopel, Sebastian, Vedaldi, Andrea, Zisserman, Andrew   +17 more
core  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Winged units of literary origin in Orthodox media texts

Opera slavica, 2020
The article is devoted to winged units dating back to Russian literature and used in the texts of modern Orthodox media discourse. Remaining one of the main sources of the winged units, literature contends for primacy with synthetic genres (cinema ...
Svetlana Viktorovna Duduškina, Ol'ga Valentinovna Lomakina, Aleksandra Stefanovna Makarova   +2 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Linguistic-culturological characteristics of a conflicting linguistic personality in modern Internet discourse

Russian Language Studies
The research is devoted to the conflictual linguistic personality of a hater as one of the types of cybercommunication which are rapidly gaining popularity, namely, hating as a purposeful type of speech aggression on the Internet.
Fluza G. Fatkullina, Saeedeh Dastamooz
doaj   +1 more source