Results 41 to 50 of about 2,426,299 (293)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Adapting Sequence to Sequence models for Text Normalization in Social Media

, 2019
Social media offer an abundant source of valuable raw data, however informal writing can quickly become a bottleneck for many natural language processing (NLP) tasks.
Lourentzou, Ismini, Manghnani, Kabir, Zhai, ChengXiang   +2 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Creative Components of Film as Social Mechanisms of Meaning Production in Mass Communication

Вісник Харківського національного університету імені В.Н. Каразіна. Серія: Соціологічні дослідження сучасного суспільства: методологія, теорія, методи
The article analyzes the creative components of film as social mechanisms for producing meanings in mass communication. Cinema is considered not only as an art form but also as a media text that encodes and transmits cultural and social meanings through ...
Oleksandra Zinchyna, Yana Kundenko
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Neologisms and borrowings in media texts

Неофилология
INTRODUCTION. The use of neologisms in modern mass media reflects the active process of changing language and speech, the vocabulary reflects people’s desire for faster communication and accelerates the transformation of language rhythm and words, which ...
A. Yu. Zubkova, E. Yu. Burdovskaya
doaj   +1 more source

AXES at TRECVid 2011 [PDF]

, 2011
The AXES project participated in the interactive known-item search task (KIS) and the interactive instance search task (INS) for TRECVid 2011. We used the same system architecture and a nearly identical user interface for both the KIS and INS tasks. Both
Aly, Robin, Arandjelovic, Relja, Beunders, Henri, Chen, Shu, Frappier, Mathieu, Jawahar, C. V., Juneja, Mayank, Lee, Hyowon, Martijn, Kleppe, McGuinness, Kevin, O'Connor, Noel E., Ordelman, Roeland, Schneider, Daniel, Schwenninger, Jochen, Smeaton, Alan F., Tschopel, Sebastian, Vedaldi, Andrea, Zisserman, Andrew   +17 more
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

The texture of a media text as its key parameter

Неофилология
INTRODUCTION. The article presents an understanding of one of the parameters of a media text – its texture – in terms of its relationship with other parameters.
T. V. Shmeleva
doaj   +1 more source

Winged units of literary origin in Orthodox media texts

Opera slavica, 2020
The article is devoted to winged units dating back to Russian literature and used in the texts of modern Orthodox media discourse. Remaining one of the main sources of the winged units, literature contends for primacy with synthetic genres (cinema ...
Svetlana Viktorovna Duduškina, Ol'ga Valentinovna Lomakina, Aleksandra Stefanovna Makarova   +2 more
doaj   +1 more source