Results 41 to 50 of about 2,442,177 (295)
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Metaphor as a means of creating a humorous effect in Bulgarian media texts
The paper is devoted to the questions of metaphor as a linguistic means and cognitive mechanism for creating a humorous effect in Bulgarian media texts. There is a similarity between the nature of metaphors and the humor, the ability of perception which ...
Elena Viktotrovna Stoyanova
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Essential Characteristics of Media Political Discourse
Introduction. The article presents an overview of the constitutive features of media political discourse. The aim of the article is to determine the essential parameters of modern Englishlanguage media-political discourse.
N. V. Stepanova
doaj +1 more source
Stylistics and rhetoric of lifestyle discourse
The purpose of the study is to identify the features of the architectonics of lifestyle discourse in terms of the organization of stylistic and rhetorical linguistic means.
S. V. Ivanova
doaj +1 more source
The specificity of Russian media neoderivatives reflecting social realia
The involvement of media speech in the society activities determines the relevance of studying the media text components in the extralinguistic aspect. The social conditionality of media neoderivatives contributes to their research in linguopragmatic and
Larisa V. Ratsiburskaya +1 more
doaj +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Civic Position in Op-Eds: Genre and Stylistic Expression in Modern Media
Mass media inform people about the most important social, cultural, and political processes. However, news coverage is seldom objective and unbiased. The way mass media assess social events influences public opinions and attitudes.
Anna V. Degaltseva +1 more
doaj +1 more source
Formational Features of the Image of Russia on the Serbian Media Platforms
Any network media platform, as an integral multifunctional multimedia system, a priori has a set of technological advantages for broadcasting socially significant information, at the same time, media text is a key element of Internet communications.
Zvjezdan Kunich +2 more
doaj +1 more source

