Results 41 to 50 of about 2,442,177 (295)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Metaphor as a means of creating a humorous effect in Bulgarian media texts

open access: yesThe European Journal of Humour Research, 2021
The paper is devoted to the questions of metaphor as a linguistic means and cognitive mechanism for creating a humorous effect in Bulgarian media texts. There is a similarity between the nature of metaphors and the humor, the ability of perception which ...
Elena Viktotrovna Stoyanova
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Essential Characteristics of Media Political Discourse

open access: yesДискурс
Introduction. The article presents an overview of the constitutive features of media political discourse. The aim of the article is to determine the essential parameters of modern Englishlanguage media-political discourse.
N. V. Stepanova
doaj   +1 more source

Stylistics and rhetoric of lifestyle discourse

open access: yesДискурс профессиональной коммуникации, 2019
The purpose of the study is to identify the features of the architectonics of lifestyle discourse in terms of the organization of stylistic and rhetorical linguistic means.
S. V. Ivanova
doaj   +1 more source

The specificity of Russian media neoderivatives reflecting social realia

open access: yesRussian Language Studies, 2021
The involvement of media speech in the society activities determines the relevance of studying the media text components in the extralinguistic aspect. The social conditionality of media neoderivatives contributes to their research in linguopragmatic and
Larisa V. Ratsiburskaya   +1 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Civic Position in Op-Eds: Genre and Stylistic Expression in Modern Media

open access: yesСибСкрипт
Mass media inform people about the most important social, cultural, and political processes. However, news coverage is seldom objective and unbiased. The way mass media assess social events influences public opinions and attitudes.
Anna V. Degaltseva   +1 more
doaj   +1 more source

Formational Features of the Image of Russia on the Serbian Media Platforms

open access: yesRUDN Journal of Studies in Literature and Journalism, 2022
Any network media platform, as an integral multifunctional multimedia system, a priori has a set of technological advantages for broadcasting socially significant information, at the same time, media text is a key element of Internet communications.
Zvjezdan Kunich   +2 more
doaj   +1 more source

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