Results 91 to 100 of about 2,910,360 (250)

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Uvod u studije mode / Intruduction to Fashion Studies

open access: yesAM: Art + Media, 2013
Though by the last decade of twentieth century the clothing sphere was observed from various one-dimensional perspectives, the accelerated development of cultural studies helped overcome all flaws of previous approaches to this demanding social and ...
Iva Jestratijević
doaj   +1 more source

Configuring Media Theory

open access: yesMedia Theory, 2017
Marc Steinberg's manifesto for Media ...
openaire   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Kritika Burioovog koncepta postprodukcije / Critique of Bourriaud’s Concept of Postproduction

open access: yesAM: Art + Media, 2013
This paper offers a critical look at Nicolas Bourriaud’s concept of post-production based on the principle of distribution, i.e. sharing. On the general level, this paper is focused on the trend of selective borrowing of certain terms from the framework ...
Tamara Đorđević
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Alternativa i njeno značenje u kontekstu poznog socijalizma Jugoslavije / Alternative and Its Meaning in the Context of Late Socialism in Yugoslavia

open access: yesAM: Art + Media, 2014
The term alternative can be theoretically interpreted in a broader cultural context, which refers to cultural otherness derived as opposed to a dominant populist framework of society.
Vanja Milovanović
doaj   +1 more source

Chasing Success: A Cultivated Reality [PDF]

open access: yes, 2018
George Gerbner’s cultivation theory claims that people who consume heavy amounts of media are more likely to be influenced by those messages to believe the media reality as opposed to actual reality.
Bevillard, Anastasia
core   +1 more source

Quantum theory of light and noise polarization in nonlinear optics

open access: yes, 2005
We present a consistent quantum theory of the electromagnetic field in nonlinearly responding causal media, with special emphasis on $\chi^{(2)}$ media. Starting from QED in linearly responding causal media, we develop a method to construct the nonlinear
A. B. U’Ren   +5 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy