Results 91 to 100 of about 6,891,477 (358)

Children's Media Use and Sleep Problems: Issues and Unanswered Questions [PDF]

open access: yes, 2008
Reviews research on the potential effect of new trends in children's media use on sleep and the effect of inadequate sleep on attention, learning, cognitive development, and psychiatric and physical health.

core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Partisan Media and Support for Radical Protest Tactics Across Ideological Lines

open access: yesInternational Journal of Communication
News coverage of protests varies widely, and public opinion on their democratic value evolves. While the protest paradigm outlines coverage norms, the hierarchy of social struggle shows that coverage favorability varies by group.
Melissa Santillana   +3 more
doaj  

Comparison between the political information consumption of the general voter and specialized audiences. The cases of the Argentinian, Spanish and Venezuelan 2015 elections

open access: yesRevista de Comunicación, 2017
Different publics consume political information in different ways. The pattern of consumption of political information varies according to the different publics, not only in their intensity of use, but also in the various communication outlets used to ...
Fernández, C. B.   +1 more
doaj   +1 more source

The Effects of Social Media Use on the Perceptions of Mental Illness Among College Students [PDF]

open access: yes, 2019
This study examined individuals’ use of and perceptions of social media networking sites (i.e. Facebook and Twitter) on their perceptions of mental illness.
Fisher, Brea
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Social Media Use and Marketing within the Orthodontic Practice in Malaysia

open access: diamond, 2022
Yasmin Kamarudin   +3 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

THE USE OF INSTRUCTIONAL MEDIA IN THE TEACHING OF ENGLISH OF THE FIFTH YEARS STUDENTS OF SDN PURWOSARI I PASURUAN IN THE ACADEMIC YEAR 2004/2005 [PDF]

open access: yes, 2005
A teacher should have a good and interesting technique in teaching. One of them can be done by using various instructional media. This research was meant to describe the kinds and the use of instructional media in the teaching of English in the ...
IKAYANTI, KRISNA
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

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