Results 111 to 120 of about 2,509,838 (314)
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Tantalisingly Close: An Archaeology of Communication Desires in Discourses of Mobile Wireless Media
, 2008 While many studies on mobile wireless communication devices predominantly take a micro-scale approach and concentrate their often ethnographically informed focus on use values, social implications, conversation strategies, changing norms and ethics ...
de Vries, I.O. +2 more
core
Computers in Human BehaviorMothers play an important role in setting the overall media culture within the home. Research suggests that children model parental behavior in many ways, including in media use habits. The current study explores profiles or patterns of maternal media use and associations between these patterns and parenting behaviors surrounding media use and parent ...
Hailey G. Holmgren +5 more
openaire +2 more sources
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Journalists views and use of social media: Cision Social Journalism Study 2012: global report [PDF]
, 2012 The annual Social Journalism Study conducted by Cision and Canterbury Christ Church University, UK, is charting the changes of how journalists and media professionals use social media for work.
Rehkopf, F. +4 more
core
Frontiers in PsychologyIntroductionAs the COVID-19 pandemic raged, controversies about governmental responses to the epidemic also emerged in China. Previous studies mainly described the phenomenon of individual differences on support for governmental responses to COVID-19 ...
Bo Miao, Hanqing Ding
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The relationship between young people, social media use and alcohol use: A prospective cohort study
Background and aims Social media use is now a significant part of modern daily life. Little is known about how social media impacts young peoples’ drinking behaviours and drinking-related consequences.
Lim, CCW +5 more
core +1 more source